Complex regional pain syndrome overview
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Complex Regional Pain Syndrome (CRPS) is a chronic progressive disease characterized by severe pain, swelling and changes in the skin. Complex regional pain syndrome (CRPS) is a chronic pain condition that can affect any area of the body, but often affects an arm or a leg.
It is important to understand that not all complex regional pain syndromes are the same. It is quite possible for example to have a post-phlebitic syndrome involving the leg that may present with skin color changes, excess pain and swelling, but has nothing to do with RSD.
The cause of this syndrome is currently unknown. Precipitating factors include underlying illness (especially vascular disease, an underlying rheumatic condition, a hidden infection or a coagulopathy in RSD cases), orthopedic injury and surgery. Although there are documented cases that have no identifiable injury to the original site in almost all cases of RSD there was an underlying event or injury.