Difference between revisions of "Complement component 9"

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{{infobox protein
 
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'''Complement component 9''' is a protein involved in the [[complement system]].<ref name="pmid7430628">{{cite journal |vauthors=Lint TF, Zeitz HJ, Gewurz H |title=Inherited deficiency of the ninth component of complement in man |journal=J. Immunol. |volume=125 |issue=5 |pages=2252–7 |date=November 1980 |pmid=7430628 |doi= |url=http://www.jimmunol.org/cgi/pmidlookup?view=long&pmid=7430628}}</ref> It is a member of the [[Complement membrane attack complex]] (MAC) and induces pores on membranes.
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'''Complement component 9''' ('''C9''') is a [[protein]] involved in the [[complement system]], which is part of the [[innate immune system]].<ref name="pmid7430628">{{cite journal |vauthors=Lint TF, Zeitz HJ, Gewurz H |title=Inherited deficiency of the ninth component of complement in man |journal=J. Immunol. |volume=125 |issue=5 |pages=2252–7 |date=November 1980 |pmid=7430628 |doi= |url=http://www.jimmunol.org/cgi/pmidlookup?view=long&pmid=7430628}}</ref> C9 is a member of the [[complement membrane attack complex]] (MAC) and induces pores on [[cell membrane]]s, causing [[lysis]]. There are 10-16 molecules of C9 in a single membrane attack complex (MAC), along with one of each of the complement components [[complement component 5|C5b]], [[complement component 6|C6]], [[complement component 7|C7]] and [[C8 complex|C8]].<ref name="Janeway 2001">{{cite web|url=https://www.ncbi.nlm.nih.gov/books/NBK27100|title=The complement system and innate immunity|last=Janeway|first=CA Jr|author2=Travers P|author3=Walport M|year=2001|work=Immunobiology: The Immune System in Health and Disease|publisher=Garland Science|accessdate=29 December 2017|location=New York|display-authors=etal}}</ref>
  
 
==References==
 
==References==

Latest revision as of 20:37, 4 January 2018

complement component 9
Identifiers
SymbolC9
Entrez735
HUGO1358
OMIM120940
RefSeqNM_001737
UniProtP02748
Other data
LocusChr. 5 p13

Complement component 9 (C9) is a protein involved in the complement system, which is part of the innate immune system.[1] C9 is a member of the complement membrane attack complex (MAC) and induces pores on cell membranes, causing lysis. There are 10-16 molecules of C9 in a single membrane attack complex (MAC), along with one of each of the complement components C5b, C6, C7 and C8.[2]

References

  1. Lint TF, Zeitz HJ, Gewurz H (November 1980). "Inherited deficiency of the ninth component of complement in man". J. Immunol. 125 (5): 2252–7. PMID 7430628.
  2. Janeway, CA Jr; Travers P; Walport M; et al. (2001). "The complement system and innate immunity". Immunobiology: The Immune System in Health and Disease. New York: Garland Science. Retrieved 29 December 2017.

External links