Codoxime
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| Clinical data | |
|---|---|
| Synonyms | Codoxime |
| Identifiers | |
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| CAS Number | |
| PubChem CID | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C20H24N2O5 |
| Molar mass | 372.415 g/mol |
| 3D model (JSmol) | |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Codoxime is an opiate analogue that is an derivative of hydrocodone, where the 6-ketone group has been replaced by carboxymethyloxime. It has primarily antitussive effects[1] and was found to have moderate potential to cause dependence in animal studies.[2]
References
- ↑ Jack Fishman. Morphinone and Codeinone Derivatives. US Patent 3153042
- ↑ Jasinski DR, Martin WR. Assessment of the dependence-producing properties of dihydrocodeinone and codoxime. Clinical Pharmacology and Therapeutics. 1967 Mar-Apr;8(2):266-70. PMID 6021586
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- Opioids
- Antitussives