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Revision as of 19:14, 12 February 2014
Synonyms / Brand Names: Antelepsin, Antilepsin , Cloazepam, Clonopin, Iktorivil , Klonopin, Klonopin rapidly disintegrating, Landsen, Rivotril
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Dosing and Administration
Seizure disorder: For adults, the initial dose for adults with seizure disorders should not exceed 1.5 mg/day divided into three doses. Maintenance dosage must be individualized for each patient depending upon response. Maximum recommended daily dose is 20 mg. For pediatric patients: the initial dose for infants and children (up to 10 years of age or 30 kg of body weight) should be between 0.01 and 0.03 mg/kg/day but not to exceed 0.05 mg/kg/day given in two or three divided doses. Dosage should be increased by no more than 0.25 to 0.5 mg every third day until a daily maintenance dose of 0.1 to 0.2 mg/kg of body weight has been reached, unless seizures are controlled or side effects preclude further increase.
Panic disorder:For adults, he initial dose for adults with panic disorder is 0.25 mg bid. An increase to the target dose for most patients of 1 mg/day may be made after 3 days. The maximum dose is 4 mg/day. For pediatric patients, there is no clinical trial experience.
FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.
Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.
Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.
Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information
Trial Resources
Ongoing Trials, Trial Results
Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.
Media Resources
Slides, Video, Images, MP3, Podcasts, etc.
Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.
International Resources
en Español
FDA Package Insert Resources
Indications
Contraindications
Side Effects
Drug Interactions
Precautions
Overdose
Instructions for Administration
How Supplied
Pharmacokinetics and Molecular Data
FDA label
FDA on Clonazepam
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Publication Resources
Most Recent Articles on Clonazepam
Review Articles on Clonazepam
Articles on Clonazepam in N Eng J Med, Lancet, BMJ
WikiDoc State of the Art Review
Textbook Information on Clonazepam
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Trial Resources
Ongoing Trials with Clonazepam at Clinical Trials.gov
Trial Results with Clonazepam
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Guidelines & Evidence Based Medicine Resources
US National Guidelines Clearinghouse on Clonazepam
Cochrane Collaboration on Clonazepam
Cost Effectiveness of Clonazepam
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Media Resources
Powerpoint Slides on Clonazepam
Images of Clonazepam
Podcasts & MP3s on Clonazepam
Videos on Clonazepam
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Patient Resources
Patient Information from National Library of Medicine
Patient Resources on Clonazepam
Discussion Groups on Clonazepam
Patient Handouts on Clonazepam
Blogs on Clonazepam
Clonazepam in the News
Clonazepam in the Marketplace
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International Resources
Clonazepam en Español
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Adapted from the FDA Package Insert.