Chondrosarcoma differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]

Overview

Chondrosarcoma must be differentiated from other diseases such as chondroma, enchondroma, osteochondroma, and osteosarcoma.

Differentiating chondrosarcoma from other Diseases

  • Chondrosarcoma must be differentiated from following bone disorders:[1][2][3][4]
Disease Malignant lesion in patients

> 40 years

chondrogenic Histology Sacral lesions in elderly Treatment is wide resection alone
Chondrosarcoma + + + +
Metastic disease + - + -
Lymphoma + - + -
Myeloma + - + -
Malignant Fibrous Histiocytoma + - + -
Secondary sarcoma + - - -
Enchondroma - + - -
Periosteal chondroma - + - -
Osteochondroma - + - -
Parosteal osteosarcoma - - - +
Adamantinoma - - - +
Chordoma - - - +
Squamous cell carcinoma - - - +

References

  1. Peabody, Terrance (2014). Orthopaedic oncology : primary and metastatic tumors of the skeletal system. Cham: Springer. ISBN 9783319073224.
  2. Czerniak, Bogdan (2016). Dorfman and Czerniak's bone tumors. Philadelphia, PA: Elsevier/Saunders. ISBN 9780323023962.
  3. Frassica FJ, Unni KK, Beabout JW, Sim FH (1986). "Dedifferentiated chondrosarcoma. A report of the clinicopathological features and treatment of seventy-eight cases". J Bone Joint Surg Am. 68 (8): 1197–205. PMID 3021775.
  4. Björnsson J, McLeod RA, Unni KK, Ilstrup DM, Pritchard DJ (1998). "Primary chondrosarcoma of long bones and limb girdles". Cancer. 83 (10): 2105–19. PMID 9827715.



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