Choline acetyltransferase
Choline acetyltransferase | |
---|---|
Identifiers | |
Symbol | CHAT |
Entrez | 1103 |
HUGO | 1912 |
OMIM | 118490 |
RefSeq | NM_020549 |
UniProt | P28329 |
Other data | |
EC number | 2.3.1.6 |
Locus | Chr. 10 q11.2 |
Overview
Choline acetyltransferase (EC 2.3.1.6) is an enzyme that is synthesized within the body of a neuron. It is then transferred to the nerve terminal via axoplasmic flow. It joins Acetyl coenzyme A to choline, resulting in the formation of the neurotransmitter acetylcholine.
It is often used as a marker, immunohistochemically, for motor neurons (motoneurons).
See also
External links
- Choline+Acetyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)