Central pontine myelinolysis natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Natural History, Complications, and Prognosis
Natural History
- The symptoms of central pontine myelinolysis typically develop immediately after injury to the neurons of the brain stem.
Complications
- Patients, with Central Pontine Myelinolysis, may have permanent neurological damages.
- Common complications of central pontine myelinolysis include:
- Locked-in syndrome
- Quadriparesis
- Walking difficulties
- Pseudobulbar palsy
- Parkinson's disease symptoms
- Pneumonia
- Coma
- Death
Prognosis
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with central pontine myelinolysis is approximately [--]%.
- Depending on the extent of the [tumor/disease progression] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with central pontine myelinolysis.
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of the tumor; [subtype of disease/malignancy] have the most favorable prognosis.