Carotid body tumor natural history, complications and prognosis: Difference between revisions

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===Complications===
===Complications===
*Carotid body tumor may result in neurovascular complications peri and post operatively.<ref name="pmid20607078">{{cite journal |vauthors=Lim JY, Kim J, Kim SH, Lee S, Lim YC, Kim JW, Choi EC |title=Surgical treatment of carotid body paragangliomas: outcomes and complications according to the shamblin classification |journal=Clin Exp Otorhinolaryngol |volume=3 |issue=2 |pages=91–5 |date=June 2010 |pmid=20607078 |pmc=2896739 |doi=10.3342/ceo.2010.3.2.91 |url=}}</ref><ref name="pmid11578296">{{cite journal |vauthors=Plukker JT, Brongers EP, Vermey A, Krikke A, van den Dungen JJ |title=Outcome of surgical treatment for carotid body paraganglioma |journal=Br J Surg |volume=88 |issue=10 |pages=1382–6 |date=October 2001 |pmid=11578296 |doi=10.1046/j.0007-1323.2001.01878.x |url=}}</ref>
*Carotid body tumor may result in neurovascular complications peri and post operatively.<ref name="pmid20607078">{{cite journal |vauthors=Lim JY, Kim J, Kim SH, Lee S, Lim YC, Kim JW, Choi EC |title=Surgical treatment of carotid body paragangliomas: outcomes and complications according to the shamblin classification |journal=Clin Exp Otorhinolaryngol |volume=3 |issue=2 |pages=91–5 |date=June 2010 |pmid=20607078 |pmc=2896739 |doi=10.3342/ceo.2010.3.2.91 |url=}}</ref><ref name="pmid11578296">{{cite journal |vauthors=Plukker JT, Brongers EP, Vermey A, Krikke A, van den Dungen JJ |title=Outcome of surgical treatment for carotid body paraganglioma |journal=Br J Surg |volume=88 |issue=10 |pages=1382–6 |date=October 2001 |pmid=11578296 |doi=10.1046/j.0007-1323.2001.01878.x |url=}}</ref>
*These complications include cranial nerve damage as well as carotid vessel involvement.
*Neurovascular complication rate differs according to the Shamblin subtype.
*Neurovascular complication rate differs according to the Shamblin subtype.
**For type I and II, the peri and post-surgical complications are low and around 0% to 3% of the cases.
**For type I and II, the peri and post-surgical complications are low and around 0% to 3% of the cases.

Revision as of 18:29, 1 April 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]

Overview

If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

OR

Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].

OR

Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.

Natural History, Complications, and Prognosis

Natural History

  • The symptoms of carotid body tumor usually develop in the fifth decade of life and start with symptoms such as slowly growing mass in the side(s) of the neck.[1]
    • In familial cases, it tends to manifest at a younger age.[2]
  • If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

Complications

  • Carotid body tumor may result in neurovascular complications peri and post operatively.[3][4]
  • These complications include cranial nerve damage as well as carotid vessel involvement.
  • Neurovascular complication rate differs according to the Shamblin subtype.
    • For type I and II, the peri and post-surgical complications are low and around 0% to 3% of the cases.
    • For Type III, it may be as high as 7% to 35% of the cases.

Prognosis

  • Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [--]%.
  • Depending on the extent of the [tumor/disease progression] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
  • The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
  • [Subtype of disease/malignancy] is associated with the most favorable prognosis.
  • The prognosis varies with the [characteristic] of the tumor; [subtype of disease/malignancy] have the most favorable prognosis.

References

  1. Lee, Ki Yeol; Oh, Yu-Whan; Noh, Hyung Jun; Lee, Yu Jin; Yong, Hwan-Seok; Kang, Eun-Young; Kim, Kyeong Ah; Lee, Nam Joon (2006). "Extraadrenal Paragangliomas of the Body: Imaging Features". American Journal of Roentgenology. 187 (2): 492–504. doi:10.2214/AJR.05.0370. ISSN 0361-803X.
  2. Burgess, Alfred; Calderon, Moises; Jafif-Cojab, Marcos; Jorge, Diego; Balanza, Ricardo (2017). "Bilateral carotid body tumor resection in a female patient". International Journal of Surgery Case Reports. 41: 387–391. doi:10.1016/j.ijscr.2017.11.019. ISSN 2210-2612.
  3. Lim JY, Kim J, Kim SH, Lee S, Lim YC, Kim JW, Choi EC (June 2010). "Surgical treatment of carotid body paragangliomas: outcomes and complications according to the shamblin classification". Clin Exp Otorhinolaryngol. 3 (2): 91–5. doi:10.3342/ceo.2010.3.2.91. PMC 2896739. PMID 20607078.
  4. Plukker JT, Brongers EP, Vermey A, Krikke A, van den Dungen JJ (October 2001). "Outcome of surgical treatment for carotid body paraganglioma". Br J Surg. 88 (10): 1382–6. doi:10.1046/j.0007-1323.2001.01878.x. PMID 11578296.

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