Cardiac amyloidosis other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]

Overview

Reduced heart rate variability due to autonomic dysfunction can be observed on Holter monitoring. This lack of variability in the heart rate has been shown to be a more consistent predictive parameter of short-term mortality in patients with AL type amyloidosis with cardiac involvement as compared to those with AA type amyloidosis.

Other Diagnostic Studies

Holter Monitoring

• Reduced heart rate variability due to autonomic dysfunction can be observed on Holter monitoring.
• Reduced heart rate variability is a predictor of 1-year mortality in cardiac amyloidosis patients.
• This lack of variability in the heart rate has been shown to be a more consistent predictive parameter of short-term mortality in patients with AL type amyloidosis with cardiac involvement as compared to those with AA type amyloidosis.