CCRL1: Difference between revisions

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Latest revision as of 19:02, 1 March 2018

C-C chemokine receptor type 11 is a protein that in humans is encoded by the CCRL1 gene.^[1]^[2]

The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. Alternatively spliced transcript variants encoding the same protein have been described.^[2]

References

↑ Khoja H, Wang G, Ng CT, Tucker J, Brown T, Shyamala V (May 2000). "Cloning of CCRL1, an orphan seven transmembrane receptor related to chemokine receptors, expressed abundantly in the heart". Gene. 246 (1–2): 229–38. doi:10.1016/S0378-1119(00)00076-7. PMID 10767544.
↑ ^2.0 ^2.1 "Entrez Gene: CCRL1 chemokine (C-C motif) receptor-like 1".

External links

Human ACKR4 genome location and ACKR4 gene details page in the UCSC Genome Browser.
Human CCR10 genome location and CCR10 gene details page in the UCSC Genome Browser.

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Bacon KB, Schall TJ, Dairaghi DJ (1998). "RANTES activation of phospholipase D in Jurkat T cells: requirement of GTP-binding proteins ARF and RhoA". J. Immunol. 160 (4): 1894–900. PMID 9469451.
Gosling J, Dairaghi DJ, Wang Y, et al. (2000). "Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK". J. Immunol. 164 (6): 2851–6. doi:10.4049/jimmunol.164.6.2851. PMID 10706668.
Schweickart VL, Epp A, Raport CJ, Gray PW (2000). "CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines". J. Biol. Chem. 275 (13): 9550–6. doi:10.1074/jbc.275.13.9550. PMID 10734104.
Schweickart VL, Epp A, Raport CJ, Gray PW (2001). "CCR11 is a functional receptor for the monocyte chemoaattractant protein family of chemokines". The Journal of Biological Chemistry. 276 (1): 856. PMID 11134065.
Townson JR, Nibbs RJ (2002). "Characterization of mouse CCX-CKR, a receptor for the lymphocyte-attracting chemokines TECK/mCCL25, SLC/mCCL21 and MIP-3beta/mCCL19: comparison to human CCX-CKR". Eur. J. Immunol. 32 (5): 1230–41. doi:10.1002/1521-4141(200205)32:5<1230::AID-IMMU1230>3.0.CO;2-L. PMID 11981810.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Comerford I, Milasta S, Morrow V, et al. (2006). "The chemokine receptor CCX-CKR mediates effective scavenging of CCL19 in vitro". Eur. J. Immunol. 36 (7): 1904–16. doi:10.1002/eji.200535716. PMID 16791897.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

[pmid10767544-1] Khoja H, Wang G, Ng CT, Tucker J, Brown T, Shyamala V (May 2000). "Cloning of CCRL1, an orphan seven transmembrane receptor related to chemokine receptors, expressed abundantly in the heart". Gene. 246 (1–2): 229–38. doi:10.1016/S0378-1119(00)00076-7. PMID 10767544.

[entrez-2] 2.0 ^2.1 "Entrez Gene: CCRL1 chemokine (C-C motif) receptor-like 1".

[1]

[2]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
-{{PBB_Controls
+'''C-C chemokine receptor type 11''' is a [[protein]] that in humans is encoded by the ''CCRL1'' [[gene]].<ref name="pmid10767544">{{cite journal | vauthors = Khoja H, Wang G, Ng CT, Tucker J, Brown T, Shyamala V | title = Cloning of CCRL1, an orphan seven transmembrane receptor related to chemokine receptors, expressed abundantly in the heart | journal = Gene | volume = 246 | issue = 1–2 | pages = 229–38 |date=May 2000 | pmid = 10767544 | pmc =  | doi =10.1016/S0378-1119(00)00076-7  }}</ref><ref name="entrez"/>
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-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Chemokine (C-C motif) receptor-like 1
- | HGNCid = 1611
- | Symbol = CCRL1
- | AltSymbols =; CCBP2; CCR10; CC-CKR-11; CCR11; CCX-CKR; CKR-11; PPR1; VSHK1
- | OMIM = 606065
- | ECnumber =
- | Homologene = 49474
- | MGIid = 2181676
- | Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0016493 |text = C-C chemokine receptor activity}}
- | Component = {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}}
- | Process = {{GNF_GO|id=GO:0006935 |text = chemotaxis}} {{GNF_GO|id=GO:0006955 |text = immune response}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 51554
-    | Hs_Ensembl =
-    | Hs_RefseqProtein = NP_057641
-    | Hs_RefseqmRNA = NM_016557
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr =
-    | Hs_GenLoc_start =
-    | Hs_GenLoc_end =
-    | Hs_Uniprot =
-    | Mm_EntrezGene = 252837
-    | Mm_Ensembl = ENSMUSG00000041748
-    | Mm_RefseqmRNA = NM_145700
-    | Mm_RefseqProtein = NP_663746
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 9
-    | Mm_GenLoc_start = 103942502
-    | Mm_GenLoc_end = 103985278
-    | Mm_Uniprot = Q924I3
-  }}
-}}
-'''Chemokine (C-C motif) receptor-like 1''', also known as '''CCRL1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CCRL1 chemokine (C-C motif) receptor-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51554| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
 {{PBB_Summary
 | section_title =
-| summary_text = The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. Alternatively spliced transcript variants encoding the same protein have been described.<ref name="entrez">{{cite web | title = Entrez Gene: CCRL1 chemokine (C-C motif) receptor-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51554| accessdate = }}</ref>
+| summary_text = The protein encoded by this gene is a member of the [[G protein-coupled receptor]] family, and is a receptor for C-C type [[chemokines]]. This receptor has been shown to bind [[dendritic cell]]- and [[T cell]]-activated chemokines including [[CCL19]]/ELC, [[CCL21]]/SLC, and [[CCL25]]/TECK. Alternatively spliced [[transcript variants]] encoding the same protein have been described.<ref name="entrez">{{cite web | title = Entrez Gene: CCRL1 chemokine (C-C motif) receptor-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51554| accessdate = }}</ref>
 }}
 ==References==
-{{reflist|2}}
+{{reflist}}
+==External links==
+* {{UCSC gene info|ACKR4}}
+* {{UCSC gene info|CCR10}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
+*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
-*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
+*{{cite journal  | vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  |display-authors=etal}}
-*{{cite journal  | author=Bacon KB, Schall TJ, Dairaghi DJ |title=RANTES activation of phospholipase D in Jurkat T cells: requirement of GTP-binding proteins ARF and RhoA. |journal=J. Immunol. |volume=160 |issue= 4 |pages= 1894-900 |year= 1998 |pmid= 9469451 |doi=  }}
+*{{cite journal  | vauthors=Bacon KB, Schall TJ, Dairaghi DJ |title=RANTES activation of phospholipase D in Jurkat T cells: requirement of GTP-binding proteins ARF and RhoA |journal=J. Immunol. |volume=160 |issue= 4 |pages= 1894–900 |year= 1998 |pmid= 9469451 |doi=  }}
-*{{cite journal  | author=Gosling J, Dairaghi DJ, Wang Y, ''et al.'' |title=Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK. |journal=J. Immunol. |volume=164 |issue= 6 |pages= 2851-6 |year= 2000 |pmid= 10706668 |doi=  }}
+*{{cite journal  | vauthors=Gosling J, Dairaghi DJ, Wang Y |title=Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK |journal=J. Immunol. |volume=164 |issue= 6 |pages= 2851–6 |year= 2000 |pmid= 10706668 |doi=  10.4049/jimmunol.164.6.2851|display-authors=etal}}
-*{{cite journal  | author=Schweickart VL, Epp A, Raport CJ, Gray PW |title=CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines. |journal=J. Biol. Chem. |volume=275 |issue= 13 |pages= 9550-6 |year= 2000 |pmid= 10734104 |doi=  }}
+*{{cite journal  | vauthors=Schweickart VL, Epp A, Raport CJ, Gray PW |title=CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines |journal=J. Biol. Chem. |volume=275 |issue= 13 |pages= 9550–6 |year= 2000 |pmid= 10734104 |doi=10.1074/jbc.275.13.9550  }}
-*{{cite journal  | author=Khoja H, Wang G, Ng CT, ''et al.'' |title=Cloning of CCRL1, an orphan seven transmembrane receptor related to chemokine receptors, expressed abundantly in the heart. |journal=Gene |volume=246 |issue= 1-2 |pages= 229-38 |year= 2000 |pmid= 10767544 |doi=  }}
+*{{cite journal  | vauthors=Schweickart VL, Epp A, Raport CJ, Gray PW |title=CCR11 is a functional receptor for the monocyte chemoaattractant protein family of chemokines |journal= The Journal of Biological Chemistry|volume=276 |issue= 1 |pages= 856 |year=  2001|pmid= 11134065 |doi=  }}
-*{{cite journal  | author=Schweickart VL, Epp A, Raport CJ, Gray PW |title=CCR11 is a functional receptor for the monocyte chemoaattractant protein family of chemokines. |journal= |volume=276 |issue= 1 |pages= 856 |year=  |pmid= 11134065 |doi=  }}
+*{{cite journal  | vauthors=Townson JR, Nibbs RJ |title=Characterization of mouse CCX-CKR, a receptor for the lymphocyte-attracting chemokines TECK/mCCL25, SLC/mCCL21 and MIP-3beta/mCCL19: comparison to human CCX-CKR |journal=Eur. J. Immunol. |volume=32 |issue= 5 |pages= 1230–41 |year= 2002 |pmid= 11981810 |doi= 10.1002/1521-4141(200205)32:5<1230::AID-IMMU1230>3.0.CO;2-L}}
-*{{cite journal  | author=Townson JR, Nibbs RJ |title=Characterization of mouse CCX-CKR, a receptor for the lymphocyte-attracting chemokines TECK/mCCL25, SLC/mCCL21 and MIP-3beta/mCCL19: comparison to human CCX-CKR. |journal=Eur. J. Immunol. |volume=32 |issue= 5 |pages= 1230-41 |year= 2002 |pmid= 11981810 |doi= 10.1002/1521-4141(200205)32:5&lt;1230::AID-IMMU1230&gt;3.0.CO;2-L }}
+*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 |display-authors=etal}}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal  | vauthors=Comerford I, Milasta S, Morrow V |title=The chemokine receptor CCX-CKR mediates effective scavenging of CCL19 in vitro |journal=Eur. J. Immunol. |volume=36 |issue= 7 |pages= 1904–16 |year= 2006 |pmid= 16791897 |doi= 10.1002/eji.200535716 |display-authors=etal}}
-*{{cite journal  | author=Comerford I, Milasta S, Morrow V, ''et al.'' |title=The chemokine receptor CCX-CKR mediates effective scavenging of CCL19 in vitro. |journal=Eur. J. Immunol. |volume=36 |issue= 7 |pages= 1904-16 |year= 2006 |pmid= 16791897 |doi= 10.1002/eji.200535716 }}
 }}
 {{refend}}
 {{NLM content}}
-{{membrane-protein-stub}}
 {{Chemokine receptors}}
+{{Chemokine receptor modulators}}
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+{{PBB_Controls
+| update_page = yes
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 [[Category:Chemokine receptors]]
-{{WikiDoc Sources}}
+{{transmembranereceptor-stub}}

CCRL1: Difference between revisions

Latest revision as of 19:02, 1 March 2018

References

External links

Further reading

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