Breast abscess differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Breast abscess should be differentiated from other diseases that cause swelling in the breast skin. These diseases are like mastitis, inflammatory breast cancer, galactocele, plugged duct, Mondor's syndrome and fibroadenoma.[1][2] [3][4][5][6][7][8][9][10][11]

Differintiating breast abscess from other diseases

Diseases Laboratory Findings Physical Examination History and Symptoms Other Findings
Culture of the discharge Biopsy Breast tenderness Skin induration Cordlike vein appearance History of trauma Nipple retraction Nipple discharge Erythema Fever Warmth Lymphadenopathy Itching
Breast abscess + - + + - + - + + + + - -
Mastitis + - + - + - + + + + + -
Inflammatory breast cancer - + + + - + - + - + + + *Peau d' orange appearance of the skin

*Metastasis is common.

Galactocele - - - - - - + - - - - - It is differentiated from other masses by US.
Mondor's syndrome + + + - Retracted breast skin and elevation of the skin may be observed.
Cellulitis - + + + - + + -
Fibroadenoma - + - - - - + *Peau d' orange skin apperance.

*Enlarged veins on the skin

Breast abscess must also be differentiated from the following conditions:


References

  1. Greydanus DE, Matytsina L, Gains M (2006). "Breast disorders in children and adolescents". Prim Care. 33 (2): 455–502. doi:10.1016/j.pop.2006.02.002. PMID 16713771.
  2. Jahanfar S, Ng CJ, Teng CL (2013). "Antibiotics for mastitis in breastfeeding women". Cochrane Database Syst Rev (2): CD005458. doi:10.1002/14651858.CD005458.pub3. PMID 23450563.
  3. Lam E, Chan T, Wiseman SM (2014). "Breast abscess: evidence based management recommendations". Expert Rev Anti Infect Ther. 12 (7): 753–62. doi:10.1586/14787210.2014.913982. PMID 24791941.
  4. Kleer CG, van Golen KL, Merajver SD (2000). "Molecular biology of breast cancer metastasis. Inflammatory breast cancer: clinical syndrome and molecular determinants". Breast Cancer Res. 2 (6): 423–9. doi:10.1186/bcr89. PMC 138665. PMID 11250736.
  5. Dawood S, Merajver SD, Viens P, Vermeulen PB, Swain SM, Buchholz TA; et al. (2011). "International expert panel on inflammatory breast cancer: consensus statement for standardized diagnosis and treatment". Ann Oncol. 22 (3): 515–23. doi:10.1093/annonc/mdq345. PMC 3105293. PMID 20603440.
  6. Jaiyesimi IA, Buzdar AU, Hortobagyi G (1992). "Inflammatory breast cancer: a review". J Clin Oncol. 10 (6): 1014–24. doi:10.1200/JCO.1992.10.6.1014. PMID 1588366.
  7. Indelicato DJ, Grobmyer SR, Newlin H, Morris CG, Haigh LS, Copeland EM; et al. (2006). "Delayed breast cellulitis: an evolving complication of breast conservation". Int J Radiat Oncol Biol Phys. 66 (5): 1339–46. doi:10.1016/j.ijrobp.2006.07.1388. PMID 17126205.
  8. Belleflamme M, Penaloza A, Thoma M, Hainaut P, Thys F (2012). "Mondor disease: a case report in ED". Am J Emerg Med. 30 (7): 1325.e1–3. doi:10.1016/j.ajem.2011.06.031. PMID 21855258.
  9. Shetty MK, Watson AB (2001). "Mondor's disease of the breast: sonographic and mammographic findings". AJR Am J Roentgenol. 177 (4): 893–6. doi:10.2214/ajr.177.4.1770893. PMID 11566698.
  10. Kadioglu H, Yildiz S, Ersoy YE, Yücel S, Müslümanoğlu M (2013). "An unusual case caused by a common reason: Mondor's disease by oral contraceptives". Int J Surg Case Rep. 4 (10): 855–7. doi:10.1016/j.ijscr.2013.07.026. PMC 3785854. PMID 23959419.
  11. Boutet G (2012). "Breast inflammation: clinical examination, aetiological pointers". Diagn Interv Imaging. 93 (2): 78–84. doi:10.1016/j.diii.2011.12.001. PMID 22305591.

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