Bone marrow disorders: Difference between revisions
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{{Family tree |boxstyle= padding: 0; background: #66CDAA; | | | | | | | B01 | | | | | | | | | | | | B02 | | | B01= <div style="width: 10em">'''[[Acquired disorders of the bone marrow]]''' </div>|B02= <div style="width: 10em">'''[[Congenital disorders of the bone marrow]]''' </div>}} | {{Family tree |boxstyle= padding: 0; background: #66CDAA; | | | | | | | B01 | | | | | | | | | | | | B02 | | | B01= <div style="width: 10em">'''[[Acquired disorders of the bone marrow]]''' </div>|B02= <div style="width: 10em">'''[[Congenital disorders of the bone marrow]]''' </div>}} | ||
{{Family tree | | | |,|-|-|-|^|-|-|-|v|-|-|-|.| | | |,|-|^|-|.| | }} | {{Family tree | | | |,|-|-|-|^|-|-|-|v|-|-|-|.| | | |,|-|^|-|.| | }} | ||
{{Family tree |boxstyle= padding: 0; background: #DCDCDC; | | | C01 | | | | | | C02 | | C03 | | C04 | | C05 | C01= <div style="width: 7em">[[ | {{Family tree |boxstyle= padding: 0; background: #DCDCDC; | | | C01 | | | | | | C02 | | C03 | | C04 | | C05 | C01= <div style="width: 7em">[[Bone Marrow Suppression|Bone marrow suppression]] </div>| C02= <div style="width: 7em">[[Acquired disorders of the bone marrow#Bone Marrow Proliferation|Bone marrow proliferation]]</div>| C03= <div style="width: 7em">[[Acquired disorders of the bone marrow#Mixed or Unclassified Disorders|Mixed or unclassified]]</div>| C04= <div style="width: 7em">[[Congenital disorders of the bone marrow#Inherited Bone Marrow Failure Syndromes|Bone marrow suppression]]</div>| C05= <div style="width: 7em">[[Congenital disorders of the bone marrow#Proliferative Bone Marrow Failure Syndromes|Bone marrow proliferation]]</div>}} | ||
{{Family tree | |,|-|^|-|.| | | |,|-|^|-|.| | | |,|-|^|-|.| | | | }} | {{Family tree | |,|-|^|-|.| | | |,|-|^|-|.| | | |,|-|^|-|.| | | | }} | ||
{{Family tree |boxstyle= padding: 0; background: #DCDCDC; | D01 | | D02 | | D03 | | D04 | | D05 | | D06 | | | D01= [[Acquired disorders of the bone marrow#Bone Marrow Suppression|Myelosuppression]]| D02= [[Acquired disorders of the bone marrow#Bone Marrow Suppression|Immunosuppression]]| D03= [[Acquired disorders of the bone marrow#Bone Marrow Proliferation|Myeloproliferation]]| D04= [[Acquired disorders of the bone marrow#Bone Marrow Proliferation|Immunoproliferation]]| D05= [[Congenital disorders of the bone marrow#Multiple Lineages Defect|Multiple lineages]]| D06= [[Congenital disorders of the bone marrow#Single Lineage Defect|Single lineage]]}} | {{Family tree |boxstyle= padding: 0; background: #DCDCDC; | D01 | | D02 | | D03 | | D04 | | D05 | | D06 | | | D01= [[Acquired disorders of the bone marrow#Bone Marrow Suppression|Myelosuppression]]| D02= [[Acquired disorders of the bone marrow#Bone Marrow Suppression|Immunosuppression]]| D03= [[Acquired disorders of the bone marrow#Bone Marrow Proliferation|Myeloproliferation]]| D04= [[Acquired disorders of the bone marrow#Bone Marrow Proliferation|Immunoproliferation]]| D05= [[Congenital disorders of the bone marrow#Multiple Lineages Defect|Multiple lineages]]| D06= [[Congenital disorders of the bone marrow#Single Lineage Defect|Single lineage]]}} | ||
Revision as of 15:06, 17 February 2015
For congenital bone marrow disorders click here.
For acquired bone marrow disorders click here.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]; Yazan Daaboul, M.D.; Serge Korjian M.D.
Overview
Bone marrow disorders are classified into congenital bone marrow disorders and acquired bone marrow disorders.
Definition of Terms
- Bone marrow suppression: Reduced numbers of cells in bone marrow
- Myelosuppression: Reduced number of myeloid lineage cells (RBC, neutrophils, basophils, eosinophils, monocytes, platelets, mastocytes)
- Immunosuppression or lymphosuppression: Reduced number of lymphoid lineage cells (T-cell, B-cell, NK cell)
- Bone marrow proliferation: Increased numbers of cells in bone marrow
- Myeloproliferation: Increased number of myeloid lineage cells (RBC, neutrophils, basophils, eosinophils, monocytes, platelets, mastocytes)
- Immunoproliferation or lymphoproliferation: Increased number of lymphoid lineage cells (T-cell, B-cell, NK cell)
Classification
Shown below is an algorithm depicting the different classes of bone marrow disorders.
| Bone Marrow Disorders | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Myelosuppression | Immunosuppression | Myeloproliferation | Immunoproliferation | Multiple lineages | Single lineage | ||||||||||||||||||||||||||||||||||||||||||||||