Bone marrow disorders: Difference between revisions

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'''''For congenital bone marrow disorders click [[congenital bone marrow disorders|here]].'''''<br>
'''''For congenital bone marrow disorders, click [[congenital bone marrow disorders|here]].'''''<br>
'''''For acquired bone marrow disorders click [[acquired bone marrow disorders|here]].'''''
'''''For acquired bone marrow disorders, click [[acquired bone marrow disorders|here]].'''''


{{CMG}}; {{AE}} {{Rim}}; {{YD}}; {{SSK}}
{{CMG}} {{AE}} {{YD}}; {{Rim}}; {{SSK}}


==Overview==
==Overview==
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==Definition of Terms==
==Definition of Terms==
* '''Bone marrow suppression''': Reduced numbers of cells in bone marrow
* '''Bone marrow suppression''': Reduced numbers of cells in the bone marrow
** '''Myelosuppression''': Reduced number of [[myeloid]] lineage cells ([[RBC]], [[neutrophils]], [[basophils]], [[eosinophils]], [[monocyte]]s, [[platelets]], [[mastocytes]])
** '''Myelosuppression''': Reduced number of [[myeloid]] lineage cells ([[RBC]], [[neutrophils]], [[basophils]], [[eosinophils]], [[monocyte]]s, [[platelets]], [[mastocytes]])
** '''Immunosuppression or lymphosuppression''': Reduced number of [[lymphoid]] lineage cells ([[T-cell]], [[B-cell]], [[NK cell]])
** '''Immunosuppression or lymphosuppression''': Reduced number of [[lymphoid]] lineage cells ([[T-cell]], [[B-cell]], [[NK cell]])


* '''Bone marrow proliferation''': Increased numbers of cells in bone marrow
* '''Bone marrow proliferation''': Increased numbers of cells in the bone marrow
** '''Myeloproliferation''': Increased number of [[myeloid]] lineage cells ([[RBC]], [[neutrophils]], [[basophils]], [[eosinophils]], [[monocyte]]s, [[platelets]], [[mastocytes]])
** '''Myeloproliferation''': Increased number of [[myeloid]] lineage cells ([[RBC]], [[neutrophils]], [[basophils]], [[eosinophils]], [[monocyte]]s, [[platelets]], [[mastocytes]])
** '''Immunoproliferation or lymphoproliferation''': Increased number of [[lymphoid]] lineage cells ([[T-cell]], [[B-cell]], [[NK cell]])
** '''Immunoproliferation or lymphoproliferation''': Increased number of [[lymphoid]] lineage cells ([[T-cell]], [[B-cell]], [[NK cell]])

Latest revision as of 23:33, 20 August 2015

For congenital bone marrow disorders, click here.
For acquired bone marrow disorders, click here.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Rim Halaby, M.D. [2]; Serge Korjian M.D.

Overview

Bone marrow disorders are classified into congenital bone marrow disorders and acquired bone marrow disorders.

Definition of Terms

Classification

Shown below is an algorithm depicting the different classes of bone marrow disorders.

 
 
 
 
 
 
 
 
 
 
 
 
 
Bone Marrow Disorders
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Myelosuppression
 
Immunosuppression
 
Myeloproliferation
 
Immunoproliferation
 
Multiple lineages
 
Single lineage
 
 

References