Biliary cystadenoma and cystadenocarcinoma: Difference between revisions

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{{Infobox_Disease |
{{Biliary cystadenoma and cystadenocarcinoma}}
  Name          = {{PAGENAME}} |
'''For patient information click [[Biliary cystadenoma and cystadenocarcinoma patient information|here]]'''
  Image          = Bililary-cystadenoma-001.jpg|
  Caption        = Biliary cystadenoma <br> (Image courtesy of RadsWiki)|
  DiseasesDB    = |
  ICD10          = |
  ICD9          = |
  ICDO          = |
  OMIM          = |
  MedlinePlus    = |
  eMedicineSubj  = |
  eMedicineTopic = |
  MeshID        = |
}}
{{SI}}
{{CMG}}
==Overview==
'''Biliary cystadenomas''' are uncommon unilocular or multilocular cystic neoplasms that may occur within the liver (infrequently found in the extrahepatic biliary tree and gallbladder).


Although biliary cystadenomas are benign tumors, they may recur after excision and have potential to develop into biliary cystadenocarcinoma.
{{CMG}};{{AE}} {{PSK}}


==Pathophysiology==
{{SK}} Cystadenoma of biliary tract; Cystadenoma of biliary tree; Cystadenoma of biliary system; Biliary cystadenomas; Hepatobiliary cystadenoma; Intrahepatic bile duct cystadenoma; Cystadenocarcinoma of biliary tract; Cystadenocarcinoma of biliary tract; Intrahepatic bile duct cystadenocarcinoma; Hepatobiliary cystadenocarcinoma; Cystadenocarcinoma of biliary system
===Microscopic Pathology===
At histologic analysis, cystadenomas have multiple loculations lined by cuboidal or columnar epithelium that resembles biliary epithelium.


==Differenting Biliary cystadenoma and cystadenocarcinoma from other Diseases==
==[[Biliary cystadenoma and cystadenocarcinoma overview|Overview]]==


The differential diagnosis principally includes
==[[Biliary cystadenoma and cystadenocarcinoma historical perspective|Historical Perspective]]==
*[[Echinococcus|Hepatic echinococcal cyst]]
*[[Liver abscess|Hepatic abscess]]


==Epidemiology and Demographics==
==[[Biliary cystadenoma and cystadenocarcinoma classification|Classification]]==


Cystadenomas occur predominantly in middle-aged women.
==[[Biliary cystadenoma and cystadenocarcinoma pathophysiology|Pathophysiology]]==


==Diagnosis==
==[[Biliary cystadenoma and cystadenocarcinoma causes|Causes]]==


===History and Symptoms===
==[[Biliary cystadenoma and cystadenocarcinoma differential diagnosis|Differentiating Biliary cystadenoma and cystadenocarcinoma from other Diseases]]==


The clinical presentation is variable, depending on the size and location of the cyst. Abdominal pain, obstructive jaundice, palpable mass, increasing abdominal girth, nausea, and vomiting are common signs and symptoms.
==[[Biliary cystadenoma and cystadenocarcinoma epidemiology and demographics|Epidemiology and Demographics]]==


Biliary cystadenomas range in size from 3 to 40 cm. Large cystadenomas may demonstrate mass effect on adjacent organs or may be associated with [[hepatomegaly]].
==[[Biliary cystadenoma and cystadenocarcinoma risk factors|Risk Factors]]==


===Computed Tomography===
==[[Biliary cystadenoma and cystadenocarcinoma screening|Screening]]==


There are no specific imaging features that permit reliable differentiation of biliary cystadenoma from cystadenocarcinoma.
==[[Biliary cystadenoma and cystadenocarcinoma natural history, complications and prognosis|Natural History, Complications and Prognosis]]==


*The CT attenuation of the fluid component in a biliary cystadenoma varies depending on the fluid content.
==Diagnosis==
*Higher attenuation may indicate recent hemorrhage.
*Calcifications that may be present in the septa or cyst wall are typically more apparent with CT than other imaging modalities.
*Septa may enhance with contrast material.
 
(Images courtesy of RadsWiki)
 
<gallery>
Image:Bililary-cystadenoma-001.jpg|CT image demonstates a biliary cystadenoma
Image:Bililary-cystadenoma-002.jpg|CT image demonstates a biliary cystadenoma
</gallery>


===MRI===
[[Biliary cystadenoma and cystadenocarcinoma staging|Staging]] | [[Biliary cystadenoma and cystadenocarcinoma history and symptoms|History and Symptoms]] | [[Biliary cystadenoma and cystadenocarcinoma physical examination|Physical Examination]] | [[Biliary cystadenoma and cystadenocarcinoma laboratory findings|Laboratory Findings]] | [[Biliary cystadenoma and cystadenocarcinoma x ray|X Ray]] | [[Biliary cystadenoma and cystadenocarcinoma CT|CT]] | [[Biliary cystadenoma and cystadenocarcinoma MRI|MRI]] | [[Biliary cystadenoma and cystadenocarcinoma echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Biliary cystadenoma and cystadenocarcinoma other imaging findings|Other Imaging Findings]] | [[Biliary cystadenoma and cystadenocarcinoma other diagnostic studies|Other Diagnostic Studies]]


There are no specific imaging features that permit reliable differentiation of biliary cystadenoma from cystadenocarcinoma.
==Treatment==


*The MR signal intensity of biliary cystadenoma is variable on both T1- and T2-weighted images, depending on the content of the cyst fluid.
[[Biliary cystadenoma and cystadenocarcinoma medical therapy|Medical Therapy]] | [[Biliary cystadenoma and cystadenocarcinoma surgery|Surgery]] | [[Biliary cystadenoma and cystadenocarcinoma primary prevention|Primary Prevention]] | [[Biliary cystadenoma and cystadenocarcinoma secondary prevention|Secondary Prevention]] | [[Biliary cystadenoma and cystadenocarcinoma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Biliary cystadenoma and cystadenocarcinoma future or investigational therapies|Future or Investigational Therapies]]


===Ultrasound===
==Case Studies==


There are no specific imaging features that permit reliable differentiation of biliary cystadenoma from cystadenocarcinoma.
[[Biliary cystadenoma and cystadenocarcinoma case study one|Case #1]]
 
*At US, a biliary cystadenoma appears as a unilocular or multilocular cyst with enhanced through transmission.
*Acoustic shadowing may be present from septal or wall calcification.
*The cyst fluid may contain low-level echoes from blood products, mucin, or proteinaceous fluid. Serous and bilious cyst fluid is generally anechoic.
*Echogenic mural nodules and papillary projections may be present.


==External Links==
==External Links==
*[http://goldminer.arrs.org/search.php?query=Biliary%20cystadenoma Goldminer: Biliary cystadenoma]
*[http://goldminer.arrs.org/search.php?query=Biliary%20cystadenoma Goldminer: Biliary cystadenoma]
*[http://goldminer.arrs.org/search.php?query=Biliary%20cystadenocarcinoma Goldminer: Biliary cystadenocarcinoma]
*[http://goldminer.arrs.org/search.php?query=Biliary%20cystadenocarcinoma Goldminer: Biliary cystadenocarcinoma]
==Reference==
{{reflist|2}}
*Angela D. Levy, Linda A. Murakata, Robert M. Abbott, and Charles A. Rohrmann, Jr. [http://radiographics.rsnajnls.org/cgi/content/abstract/22/2/387 From the Archives of the AFIP: Benign Tumors and Tumorlike Lesions of the Gallbladder and Extrahepatic Bile Ducts: Radiologic-Pathologic Correlation.] RadioGraphics 2002 22: 387-413.
*Angela D. Levy, Linda A. Murakata, Robert M. Abbott, and Charles A. Rohrmann, Jr. [http://radiographics.rsnajnls.org/cgi/content/abstract/22/2/387 From the Archives of the AFIP: Benign Tumors and Tumorlike Lesions of the Gallbladder and Extrahepatic Bile Ducts: Radiologic-Pathologic Correlation.] RadioGraphics 2002 22: 387-413.


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Latest revision as of 02:28, 6 November 2017

Biliary cystadenoma and cystadenocarcinoma Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Biliary cystadenoma and cystadenocarcinoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

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Treatment

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Primary Prevention

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]

Synonyms and keywords: Cystadenoma of biliary tract; Cystadenoma of biliary tree; Cystadenoma of biliary system; Biliary cystadenomas; Hepatobiliary cystadenoma; Intrahepatic bile duct cystadenoma; Cystadenocarcinoma of biliary tract; Cystadenocarcinoma of biliary tract; Intrahepatic bile duct cystadenocarcinoma; Hepatobiliary cystadenocarcinoma; Cystadenocarcinoma of biliary system

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Biliary cystadenoma and cystadenocarcinoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging | History and Symptoms | Physical Examination | Laboratory Findings | X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

External Links

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