Bartonella quintana: Difference between revisions
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==Overview== | ==Overview== | ||
'''''Bartonella quintana''''', also known as ''Rochalimaea quintana'',<ref name="medterms">{{cite web |url=http://www.medterms.com/script/main/art.asp?articlekey=8096 |title=''Bartonella quintana'' definition - Medical Dictionary definitions of popular medical terms|accessdate=2007-06-10 |format=Html |work= Medical Dictionary definitions of popular medical terms}}</ref> is a [[microorganism]] that is transmitted by the [[human body louse]].<ref name="cdc">{{cite web |url=http://www.cdc.gov/ncidod/eid/vol11no12/03-0045.htm |title=''Bartonella quintana'' in Cynomolgus Monkey |accessdate=2007-06-10 |author=Laurie G. O'Rourke |coauthors=Christian Pitulle, Barbara C. Hegarty, Sharon Kraycirik, Karen A. Killary, Paul Grosenstein, James W. Brown, Edward B. Breitschwerdt |year=2005 |month=December |format=Htm |work=Centers for Disease Control and Prevention |publisher=Centers for Disease Control and Prevention Centers for Disease Control and Prevention }}</ref> This microorganism is [[trench fever]]'s etiologic agent.<ref name="cdc"/> This [[bacteria]] resulted in about 1 million soldiers in Europe during World War I being infected with Trench Fever.<ref name="cdc2">{{cite web |url=http://www.cdc.gov/ncidod/eid/vol2no2/jackson.htm |title=Emergence of ''Bartonella quintana'' Infection among Homeless Persons |accessdate=2007-06-11 |format=htm |work=Centers for Disease Control and Prevention }}</ref> | '''''Bartonella quintana''''', also known as ''Rochalimaea quintana'',<ref name="medterms">{{cite web |url=http://www.medterms.com/script/main/art.asp?articlekey=8096 |title=''Bartonella quintana'' definition - Medical Dictionary definitions of popular medical terms|accessdate=2007-06-10 |format=Html |work= Medical Dictionary definitions of popular medical terms}}</ref> is a [[microorganism]] that is transmitted by the [[human body louse]].<ref name="cdc">{{cite web |url=http://www.cdc.gov/ncidod/eid/vol11no12/03-0045.htm |title=''Bartonella quintana'' in Cynomolgus Monkey |accessdate=2007-06-10 |author=Laurie G. O'Rourke |coauthors=Christian Pitulle, Barbara C. Hegarty, Sharon Kraycirik, Karen A. Killary, Paul Grosenstein, James W. Brown, Edward B. Breitschwerdt |year=2005 |month=December |format=Htm |work=Centers for Disease Control and Prevention |publisher=Centers for Disease Control and Prevention Centers for Disease Control and Prevention }}</ref> This microorganism is [[trench fever]]'s etiologic agent.<ref name="cdc"/> This [[bacteria]] resulted in about 1 million soldiers in Europe during World War I being infected with Trench Fever.<ref name="cdc2">{{cite web |url=http://www.cdc.gov/ncidod/eid/vol2no2/jackson.htm |title=Emergence of ''Bartonella quintana'' Infection among Homeless Persons |accessdate=2007-06-11 |format=htm |work=Centers for Disease Control and Prevention }}</ref> | ||
==Antimicrobial regimen== | |||
::* 1. '''Bartonella quintana''' | |||
:::* 1.1 '''Acute or chronic infections without endocarditis'''<ref name="pmid12821469">{{cite journal| author=Foucault C, Raoult D, Brouqui P| title=Randomized open trial of gentamicin and doxycycline for eradication of Bartonella quintana from blood in patients with chronic bacteremia. | journal=Antimicrob Agents Chemother | year= 2003 | volume= 47 | issue= 7 | pages= 2204-7 | pmid=12821469 | doi= | pmc=PMC161867 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12821469 }} </ref> | |||
::::* Preferred regimen: [[Doxycycline]] 200 mg PO qd or 100 mg bid for 4 weeks {{and}} [[Gentamicin]] 3 mg/kg IV qd for the first 2 weeks | |||
:::* 1.2 '''Endocarditis'''<ref name="pmid15956145">{{cite journal| author=Baddour LM, Wilson WR, Bayer AS, Fowler VG, Bolger AF, Levison ME et al.| title=Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America. | journal=Circulation | year= 2005 | volume= 111 | issue= 23 | pages= e394-434 | pmid=15956145 | doi=10.1161/CIRCULATIONAHA.105.165564 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15956145 }} </ref> | |||
::::* Preferred regimen: [[Gentamicin]] 3 mg/kg/day IV q8h for 14 days {{and}} [[Ceftriaxone]] 2 g IV q24h for 6 weeks {{withorwithout}} [[Doxycycline]] 100 mg PO bid for 6 weeks | |||
==References== | ==References== | ||
Revision as of 17:21, 28 July 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Bartonella quintana, also known as Rochalimaea quintana,[1] is a microorganism that is transmitted by the human body louse.[2] This microorganism is trench fever's etiologic agent.[2] This bacteria resulted in about 1 million soldiers in Europe during World War I being infected with Trench Fever.[3]
Antimicrobial regimen
- 1. Bartonella quintana
- 1.1 Acute or chronic infections without endocarditis[4]
- Preferred regimen: Doxycycline 200 mg PO qd or 100 mg bid for 4 weeks AND Gentamicin 3 mg/kg IV qd for the first 2 weeks
- 1.2 Endocarditis[5]
- Preferred regimen: Gentamicin 3 mg/kg/day IV q8h for 14 days AND Ceftriaxone 2 g IV q24h for 6 weeks ± Doxycycline 100 mg PO bid for 6 weeks
References
- ↑ "Bartonella quintana definition - Medical Dictionary definitions of popular medical terms" (Html). Medical Dictionary definitions of popular medical terms. Retrieved 2007-06-10.
- ↑ 2.0 2.1 Laurie G. O'Rourke (2005). "Bartonella quintana in Cynomolgus Monkey" (Htm). Centers for Disease Control and Prevention. Centers for Disease Control and Prevention Centers for Disease Control and Prevention. Retrieved 2007-06-10. Unknown parameter
|month=ignored (help); Unknown parameter|coauthors=ignored (help) - ↑ "Emergence of Bartonella quintana Infection among Homeless Persons" (htm). Centers for Disease Control and Prevention. Retrieved 2007-06-11.
- ↑ Foucault C, Raoult D, Brouqui P (2003). "Randomized open trial of gentamicin and doxycycline for eradication of Bartonella quintana from blood in patients with chronic bacteremia". Antimicrob Agents Chemother. 47 (7): 2204–7. PMC 161867. PMID 12821469.
- ↑ Baddour LM, Wilson WR, Bayer AS, Fowler VG, Bolger AF, Levison ME; et al. (2005). "Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America". Circulation. 111 (23): e394–434. doi:10.1161/CIRCULATIONAHA.105.165564. PMID 15956145.