Ascariasis overview: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
Ascariasis has been around for several years and the scientific study of Ascaris lumbricoides was promoted by Edward Tyson.<ref name="pmid15463076">{{cite journal| author=Crompton DW| title=The prevalence of Ascariasis. | journal=Parasitol Today | year= 1988 | volume= 4 | issue= 6 | pages= 162-9 | pmid=15463076 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15463076 }} </ref> | Ascariasis has been around for several years and the scientific study of Ascaris lumbricoides was promoted by Edward Tyson.<ref name="pmid15463076">{{cite journal| author=Crompton DW| title=The prevalence of Ascariasis. | journal=Parasitol Today | year= 1988 | volume= 4 | issue= 6 | pages= 162-9 | pmid=15463076 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15463076 }} </ref> | ||
==Pathophysiology== | ==Pathophysiology<ref name="Murray and Nadel's Textbook of Respiratory Medicine">Kim, Kami; Weiss, Louis; Tanowitz, Herbert (2016). "Chapter 39:Parasitic Infections". Murray and Nadel's Textbook of Respiratory Medicine Sixth Edition. Elsevier. pp. 682–698. ISBN 978-1-4557-3383-5.</ref> The pathogenesis of ascariasis involves the following processes:<ref name="Murray and Nadel's Textbook of Respiratory Medicine" /><ref name="Ferri's Clinical Advisor">Ferri, Fred (2017). "Chapter:Ascariasis". Ferri's Clinical Advisor 2017. Elsevier. pp. 117–117. ISBN 978-0-3232-8048-8.</ref><ref name="Nelson Textbook of Pediatrics">Kliegman, Robert; Stanton, Bonita; St. Geme, Joseph; Schor, Nina (2016). "Chapter 291:Ascariasis (Ascaris lumbricoides)". Nelson Textbook of Pediatrics Twentieth Edition. Elsevier. pp. 1733–1734. ISBN 978-1-4557-7566-8.</ref>== | ||
The transmission of infection is usually from hand to mouth, and humans are the only known host. Following ingestion of infective eggs, larvae hatch and invade the intestinal mucosa. The larvae are carried via the portal, then systemic circulation to the lungs. The larvae mature further in the lungs, penetrate the alveolar walls, and ascend the bronchial tree to the throat. The larvae are then swallowed. Upon reaching the small intestine, they develop into adult worms. The adult worms can live for 1 to 2 years. | The transmission of infection is usually from hand to mouth, and humans are the only known host. Following ingestion of infective eggs, larvae hatch and invade the intestinal mucosa. The larvae are carried via the portal, then systemic circulation to the lungs. The larvae mature further in the lungs, penetrate the alveolar walls, and ascend the bronchial tree to the throat. The larvae are then swallowed. Upon reaching the small intestine, they develop into adult worms. The adult worms can live for 1 to 2 years. | ||
Revision as of 15:22, 7 March 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Fatimo Biobaku M.B.B.S [2]
Overview
Ascariasis is a globally occurring helminthic infection of humans.[1] is the most common human helminth infection.[2] The transmission of infection is usually from hand to mouth, and humans are the only known host.[2] Ascariasis is more common in tropical areas of the world and predominantly affects the pediatric age group.[3]
Historical Perspective
Ascariasis has been around for several years and the scientific study of Ascaris lumbricoides was promoted by Edward Tyson.[4]
Pathophysiology[2] The pathogenesis of ascariasis involves the following processes:[2][3][1]
The transmission of infection is usually from hand to mouth, and humans are the only known host. Following ingestion of infective eggs, larvae hatch and invade the intestinal mucosa. The larvae are carried via the portal, then systemic circulation to the lungs. The larvae mature further in the lungs, penetrate the alveolar walls, and ascend the bronchial tree to the throat. The larvae are then swallowed. Upon reaching the small intestine, they develop into adult worms. The adult worms can live for 1 to 2 years.
Causes
Ascariasis is a soil helminth infection caused by the nematode Ascaris lumbricoides.[2]
Differentiating Ascariasis from other Diseases
Ascariasis can mimic other worm infections, and also gastrointestinal pathologies like peptic ulcer disease, intussusception in children, bile duct stone, etc.[5][6]
Epidemiology and Demographics
Ascariasis affects at least 1 billion people worldwide and about 4 million people in the United States.[3] It is more common in the pediatric age group (ages 2-10 years).[3] Ascariasis is three times more common in African-Americans compared to Caucasians.[3]
Risk factors
Natural History, Complications and Prognosis
History and Symptoms
Physical Examination
Laboratory Findings
X ray
CT
Ultrasound
Other Diagnostic Studies
Medical Therapy
Surgery
References
- ↑ 1.0 1.1 Kliegman, Robert; Stanton, Bonita; St. Geme, Joseph; Schor, Nina (2016). "Chapter 291:Ascariasis (Ascaris lumbricoides)". Nelson Textbook of Pediatrics Twentieth Edition. Elsevier. pp. 1733–1734. ISBN 978-1-4557-7566-8.
- ↑ 2.0 2.1 2.2 2.3 2.4 Kim, Kami; Weiss, Louis; Tanowitz, Herbert (2016). "Chapter 39:Parasitic Infections". Murray and Nadel's Textbook of Respiratory Medicine Sixth Edition. Elsevier. pp. 682–698. ISBN 978-1-4557-3383-5.
- ↑ 3.0 3.1 3.2 3.3 3.4 Ferri, Fred (2017). "Chapter:Ascariasis". Ferri's Clinical Advisor 2017. Elsevier. pp. 117–117. ISBN 978-0-3232-8048-8.
- ↑ Crompton DW (1988). "The prevalence of Ascariasis". Parasitol Today. 4 (6): 162–9. PMID 15463076.
- ↑ Hamed AD, Akinola O (1990). "Intestinal ascariasis in the differential diagnosis of peptic ulcer disease". Trop Geogr Med. 42 (1): 37–40. PMID 2260195.
- ↑ Goel A, Lakshmi CP, Pottakkat B (2012). "Biliary ascariasis: mimicker of retained bile duct stone". Dig Endosc. 24 (6): 480. doi:10.1111/j.1443-1661.2012.01338.x. PMID 23078449.