Appendicular abscess pathophysiology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

An appendicular abscess is a complication of acute appendicitis. It is resulted due to the invasion of the appendix by bacteria following an obstruction. The appendix exists at the junction of the small and large intestine and is a natural habitat of wide variety of bacteria. It is, therefore, prone to develop complications when blocked. Coupled with an infection, acute appendicitis can be life threatening. Other serious complications which may develop as a result of neglected appendicitis or appendicular abscess include gangrene, appendicular masses, rupture, and general peritoneal infections.

Pathophysiology

Transmission

Duration

  • The risk of perforation or abscess formation is negligible within the first 12 hours of untreated symptoms, but then increases to 8.0% within the first 24 h.[1]

Gross Pathology

Microscopic findings

References

  1. 1.0 1.1 Bradley EL, Isaacs J (1978). "Appendiceal abscess revisited". Arch Surg. 113 (2): 130–2. PMID 626573.
  2. Wangensteen OH, Bowers WF. Significance of the obstructive factor in the genesis of acute appendicitis. Arch Surg 1937;34:496-526