Anti-NMDA receptor encephalitis MRI

Anti-NMDA receptor encephalitis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Key MRI Findings for Anti-NMDA Receptor Encephalitis

In fifty percent of instances, magnetic resonance (MR) imaging of the brain is unremarkable. In the remaining 50%, MR Imaging may demonstrate nonspecific T2 or fluid-attenuated inversion recovery (FLAIR) signal hyperintensity in the hippocampus; cerebellar, frontobasal, or insular cortex; basal ganglia; brainstem; and, rarely, the spinal cord.

Anti-NMDAR encephalitis is notoriously difficult to diagnose based only on neuroimaging characteristics, as there are no discernible patterns of brain involvement