Anaplastic large cell lymphoma differential diagnosis: Difference between revisions

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{{Anaplastic large cell lymphoma}}
[[Image:Home_logo1.png|right|250px|link=http://www.wikidoc.org/index.php/Anaplastic_large_cell_lymphoma]]
{{CMG}}
{{CMG}}; {{AE}} {{AS}}
==Differential diagnosis==
==Overview==
*As the appearance of the hallmark cells, pattern of growth (nesting within lymph nodes) and positivity for EMA may mimic [[metastatic]] [[carcinoma]], it is important to include markers for [[cytokeratin]] in any diagnostic panel (these will be negative in the case of anaplastic lymphoma).
 
*Other mimics include CD30 positive B-cell lymphomas with anaplastic cells (including Hodgkin lymphomas).  These are identified by their positivity for markers of B-cell lineage and frequent presence of markers of EBV.
==Differential Diagnosis==
*Primary cutaneous T-cell lymphomas may also be positive for CD30; these are excluded by their anatomic distribution. ALK positivity may also be seen in some large cell B-cell lymphomas and occasionally in [[rhabdomyosarcoma]]s.


==References==
==References==
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{{reflist|2}}
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[[Category:Hematology]]
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[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Hematology]]
[[Category:Immunology]]

Latest revision as of 20:31, 28 February 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

Differential Diagnosis

References

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