Anaplastic large cell lymphoma differential diagnosis: Difference between revisions

Latest revision as of 20:31, 28 February 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

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 __NOTOC__
-{{Anaplastic large cell lymphoma}}
+[[Image:Home_logo1.png|right|250px|link=http://www.wikidoc.org/index.php/Anaplastic_large_cell_lymphoma]]
-{{CMG}}
+{{CMG}}; {{AE}} {{AS}}
-==Differential diagnosis==
+==Overview==
-*As the appearance of the hallmark cells, pattern of growth (nesting within lymph nodes) and positivity for EMA may mimic [[metastatic]] [[carcinoma]], it is important to include markers for [[cytokeratin]] in any diagnostic panel (these will be negative in the case of anaplastic lymphoma).
-*Other mimics include CD30 positive B-cell lymphomas with anaplastic cells (including Hodgkin lymphomas).  These are identified by their positivity for markers of B-cell lineage and frequent presence of markers of EBV.
+==Differential Diagnosis==
-*Primary cutaneous T-cell lymphomas may also be positive for CD30; these are excluded by their anatomic distribution. ALK positivity may also be seen in some large cell B-cell lymphomas and occasionally in [[rhabdomyosarcoma]]s.
 ==References==
 {{reflist|2}}
 {{WH}}
 {{WS}}
 [[Category:Hematology]]
 [[Category:Types of cancer]]
+ [[Category:Up-To-Date]]
 [[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Hematology]]
+[[Category:Immunology]]