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{{drugbox
<div style="float: right;">
| IUPAC_name        = ''N''-[(1-allylpyrrolidin-2-yl)methyl]-6-methoxy-<br>1''H''-benzotriazole-5-carboxamide
[[File:Alizapride.png|thumb|none|400px|This image is provided by the National Library of Medicine.]]</div>
| image            = Alizapride.svg
__NOTOC__
| CAS_number        = 59338-93-1
{{SI}}
| ATC_prefix        = A03
{{CMG}}
| ATC_suffix        = FA05
==Overview==
| PubChem          = 43008
'''Alizapride''' ('''Litican''', '''Plitican''', '''Superan''', '''Vergentan''') is a [[dopamine antagonist]] with [[prokinetic]] and [[antiemetic]] effects used in the treatment of [[nausea]] and [[vomiting]], including [[postoperative nausea and vomiting]]. It is structurally related to [[metoclopramide]] and other [[benzamide]]s.<ref>{{cite journal |author=Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M |title=Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial |journal=Cancer Chemother Pharmacol |volume=22 |issue=4 |pages=316–20 |year=1988 |pmid=3048762 |doi=10.1007/bf00254238}}</ref>
| DrugBank          =
| C=16|H=21|N=5|O=2
| molecular_weight  = 315.37 g/mol
| bioavailability  =  
| protein_bound    =  
| metabolism        =  
| elimination_half-life = 3 hours
| excretion        = [[Kidney|Renal]]
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      = <!-- A / B            / C / D / X -->
| pregnancy_category=
| legal_AU          = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA          = <!--            / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK          = <!-- GSL        / P      / POM / CD / Class A, B, C -->
| legal_US          = <!-- OTC                  / Rx-only  / Schedule I, II, III, IV, V -->
| legal_status      =  
| routes_of_administration = Oral, [[intramuscular injection|intramuscular]], [[intravenous therapy|intravenous]]
}}


{{Editor Help}}
== See also ==
* [[Antiemetic]]
* [[Benzamide]]
[[File:Alizapride1.png|thumb|none|400px|This image is provided by the National Library of Medicine.]]


'''Alizapride''' is a [[dopamine antagonist]] with [[prokinetic]] and [[antiemetic]] effects used in the treatment of [[nausea]] and [[vomiting]], including [[postoperative nausea and vomiting]]. It is  structurally related to [[metoclopramide]].<ref>{{cite journal |author=Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M |title=Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial |journal=Cancer Chemother Pharmacol |volume=22 |issue=4 |pages=316–20 |year=1988 |pmid=3048762 |doi=}}</ref>
== References ==
{{Reflist|2}}


Alizapride is marketed under various trade names including '''Plitican''', '''Superan''' and '''Vergentan'''.<ref>{{fr icon}} {{cite web | url = http://www.biam2.org/www/Sub4814.html | title = Alizapride Chlorhydrate | date = [[June 2]] [[1997]] | accessdate = 2007-08-14 | publisher = BIAM}}</ref>
{{Propulsives}}


==References==
{{Reflist}}
{{Drugs for functional gastrointestinal disorders}}
{{WikiDoc Help Menu}}
[[Category:Pharmacology]]
[[Category:Antiemetics]]
[[Category:Antiemetics]]
[[Category:Dopamine antagonists]]
[[Category:Dopamine antagonists]]
[[Category:Motility stimulants]]
[[Category:Motility stimulants]]
[[Category:Drugs]]
[[Category:Phenol ethers]]
[[Category:Pyrrolidines]]
[[Category:Drug]]

Latest revision as of 14:36, 8 April 2015

This image is provided by the National Library of Medicine.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Alizapride (Litican, Plitican, Superan, Vergentan) is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is structurally related to metoclopramide and other benzamides.[1]

See also

This image is provided by the National Library of Medicine.

References

  1. Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M (1988). "Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial". Cancer Chemother Pharmacol. 22 (4): 316–20. doi:10.1007/bf00254238. PMID 3048762.

Template:Propulsives