Adult T-cell leukemia physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

Patients with adult T-cell leukemia usually appear lethargic and fatigued. Physical examination of patients with adult T-cell leukemia is usually remarkable for maculopapular rash, skin ulceration, and splenomegaly.

Physical Examination

General Appearance

• Adult T-cell leukemia patients often appear lethargic and fatigued

Vital Signs

• Low grade fever

Skin

• Maculopapular rash
• Skin ulceration
• Leukemia cutis (infiltration of skin by leukemic cells)

HEENT

• Lymphadenopathy

Abdomen

• Splenomegaly
• Hepatomegaly

Cardiac

• Tachycardia
• Abnormal heart rhythm may be present

Skeletal

• Muscle wasting