Adiposogenital dystrophy causes

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Template:Adiposogenital Dystrophy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Ogechukwu Hannah Nnabude, MD

Overview

There are various types of lesion that can lead to adiposogenital dystrophy, most of which result from an injury of a part of the arcuate nucleus and ventromedial nuclei of the hypothalamus. Deep brain stimulation has also been seen to produce similar symptoms in patients with Parkinson's disease.

Causes

  • Deep brain stimulation [5] [6]. Some patients were observed to have an increase in weight of up to 20kg[7].
  • Other causes of adiposogenital dystrophy include Friedreich ataxia, demyelinating diseases, and microcephaly[8]


  1. Aulakh R, Chopra S (2018). "Pediatric Tubercular Meningitis: A Review". J Pediatr Neurosci. 13 (4): 373–382. doi:10.4103/JPN.JPN_78_18. PMC 6413593. PMID 30937075.
  2. Babinski-fröhlich syndrome. Bissonnette B, & Luginbuehl I, & Marciniak B, & Dalens B.J.(Eds.), (2006). Syndromes: Rapid Recognition and Perioperative Implications. McGraw Hill. https://accessanesthesiology.mhmedical.com/content.aspx?bookid=852&sectionid=49517244
  3. Molina A, Mañá J, Villabona C, Fernández-Castañer M, Soler J (2002). "Hypothalamic-pituitary sarcoidosis with hypopituitarism. Long-term remission with methylprednisolone pulse therapy". Pituitary. 5 (1): 33–6. doi:10.1023/a:1022153401880. PMID 12638724.
  4. Belojevic G, Maric-Zivkovic J (2005) Sarcoidosis and obesity. Med Pregl 58(Suppl 1):44–45 Medline
  5. Tuite PJ, Maxwell RE, Ikramuddin S, Kotz CM, Kotzd CM, Billington CJ; et al. (2005). "Weight and body mass index in Parkinson's disease patients after deep brain stimulation surgery". Parkinsonism Relat Disord. 11 (4): 247–52. doi:10.1016/j.parkreldis.2005.01.006. PMID 15878586.
  6. Romito LM, Scerrati M, Contarino MF, Iacoangeli M, Bentivoglio AR, Albanese A (2003) Bilateral high frequency subthalamic stimulation in Parkinson’s disease: long-term neurological follow-up. J Neurosurg Sci 47:119–128 Medline
  7. Montaurier C, Morio B, Bannier S, Derost P, Arnaud P, Brandolini-Bunlon M; et al. (2007). "Mechanisms of body weight gain in patients with Parkinson's disease after subthalamic stimulation". Brain. 130 (Pt 7): 1808–18. doi:10.1093/brain/awm113. PMID 17535833.
  8. Babinski-fröhlich syndrome. Bissonnette B, & Luginbuehl I, & Marciniak B, & Dalens B.J.(Eds.), (2006). Syndromes: Rapid Recognition and Perioperative Implications. McGraw Hill. https://accessanesthesiology.mhmedical.com/content.aspx?bookid=852&sectionid=49517244

References