Acute pancreatitis surgery: Difference between revisions
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=== Indications === | === Indications === | ||
Surgery is indicated for | Surgery is indicated for:<ref name="pmid20410514">{{cite journal| author=van Santvoort HC, Besselink MG, Bakker OJ, Hofker HS, Boermeester MA, Dejong CH et al.| title=A step-up approach or open necrosectomy for necrotizing pancreatitis. | journal=N Engl J Med | year= 2010 | volume= 362 | issue= 16 | pages= 1491-502 | pmid=20410514 | doi=10.1056/NEJMoa0908821 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20410514 }} </ref><ref name="pmid22416101">{{cite journal| author=Bakker OJ, van Santvoort HC, van Brunschot S, Geskus RB, Besselink MG, Bollen TL et al.| title=Endoscopic transgastric vs surgical necrosectomy for infected necrotizing pancreatitis: a randomized trial. | journal=JAMA | year= 2012 | volume= 307 | issue= 10 | pages= 1053-61 | pmid=22416101 | doi=10.1001/jama.2012.276 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22416101 }} </ref> | ||
# Infected pancreatic necrosis | # Infected pancreatic necrosis | ||
# Diagnostic uncertainty | # Diagnostic uncertainty | ||
Revision as of 01:35, 27 November 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]
Overview
Surgery in the treatment of acute pancreatitis is indicated for infected pancreatic necrosis, in cases of diagnostic uncertainty and in the presence of complications.
Surgery
Indications
Surgery is indicated for:[1][2]
- Infected pancreatic necrosis
- Diagnostic uncertainty
- Complications.
The most common cause of death in acute pancreatitis is secondary infection. Infection is diagnosed based on 2 criteria:
- Gas bubbles on CT scan (present in 20 to 50% of infected necrosis)
- Positive bacterial culture on FNA (fine needle aspiration, usually CT or US guided) of the pancreas.
Surgical options for infected necrosis include:
- Conventional management - necrosectomy with simple drainage
- Closed management - necrosectomy with closed continuous lavage
- Open management - necrosectomy with planned staged reoperations at definite intervals (up to 7 reoperations in some cases)
Minimally Invasive Approach
Endoscopic Retrograde Cholangiopancreatography
ERCP is indicated in patients with acute pancreatitis where gallstones are the underlying cause. This includes patients with cholangitis or choledocholithiasis secondary to gallstones and have clinical findings suggestive of bile duct obstruction. It is not indicated in the absence of the aforementioned features.
ERCP is additionally indicated in cases of necrotizing pancreatitis which progressed to walled off necrosis. This typically occurs after 4-6 weeks. ERCP intervention is typically and ideally delayed to the point of walled off necrosis whenever possible when the patient is stable. In the interim, antiobiotic therapy may sustain the patient in cases of infected necrosis.[3][4][1][2]
Percutaneous Drainage
In patients who are not stable (e.g. develop sepsis or hemodynamic instability), placement of a percutaneous drain for peripancreatic fluid collection is often sufficient to reduce sepsis and afford the pancreas time to develop an operable walled-off-necrosis.[3][4][1][2]
Other Approaches
Other minimally invasive approaches may be considered such as laparoscopy, and retroperitoneal approach.[4][2]
Open Surgery
In 40% of patients, minimally invasive surgery is not achievable, traditional open necrosectomy may be considered.[1][2]
References
- ↑ 1.0 1.1 1.2 1.3 van Santvoort HC, Besselink MG, Bakker OJ, Hofker HS, Boermeester MA, Dejong CH; et al. (2010). "A step-up approach or open necrosectomy for necrotizing pancreatitis". N Engl J Med. 362 (16): 1491–502. doi:10.1056/NEJMoa0908821. PMID 20410514.
- ↑ 2.0 2.1 2.2 2.3 2.4 Bakker OJ, van Santvoort HC, van Brunschot S, Geskus RB, Besselink MG, Bollen TL; et al. (2012). "Endoscopic transgastric vs surgical necrosectomy for infected necrotizing pancreatitis: a randomized trial". JAMA. 307 (10): 1053–61. doi:10.1001/jama.2012.276. PMID 22416101.
- ↑ 3.0 3.1 van Santvoort HC, Bakker OJ, Bollen TL, Besselink MG, Ahmed Ali U, Schrijver AM; et al. (2011). "A conservative and minimally invasive approach to necrotizing pancreatitis improves outcome". Gastroenterology. 141 (4): 1254–63. doi:10.1053/j.gastro.2011.06.073. PMID 21741922.
- ↑ 4.0 4.1 4.2 Freeman ML, Werner J, van Santvoort HC, Baron TH, Besselink MG, Windsor JA; et al. (2012). "Interventions for necrotizing pancreatitis: summary of a multidisciplinary consensus conference". Pancreas. 41 (8): 1176–94. doi:10.1097/MPA.0b013e318269c660. PMID 23086243.