Abdominal angina pathophysiology: Difference between revisions

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*Abdominal angina occurs due to narrowing of the mesenteric vessels that causes decreased blood flow.<ref name="urlAbdominal Angina - StatPearls - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK441943/ |title=Abdominal Angina - StatPearls - NCBI Bookshelf |format= |work= |accessdate=}}</ref>  
*Abdominal angina occurs due to narrowing of the mesenteric vessels that causes decreased blood flow.<ref name="urlAbdominal Angina - StatPearls - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK441943/ |title=Abdominal Angina - StatPearls - NCBI Bookshelf |format= |work= |accessdate=}}</ref>  
*Atherosclerotic vascular disease at ostia of the mesenteric vessels is the most common cause of abdominal angina . Superior mesenteric artery occlusion is often found in patients presenting symptomatic occlusive mesenteric ischemia. Patients with abdominal angina are unable to increase flow in the mesenteric vessels in response to eating that's why they develop postprandial pain.<ref name="urlAbdominal Angina - StatPearls - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK441943/ |title=Abdominal Angina - StatPearls - NCBI Bookshelf |format= |work= |accessdate=}}</ref>
*Atherosclerotic vascular disease at ostia of the mesenteric vessels is the most common cause of abdominal angina . Superior mesenteric artery occlusion is often found in patients presenting symptomatic occlusive mesenteric ischemia. Patients with abdominal angina are unable to increase flow in the mesenteric vessels in response to eating that's why they develop postprandial pain.<ref name="urlAbdominal Angina - StatPearls - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK441943/ |title=Abdominal Angina - StatPearls - NCBI Bookshelf |format= |work= |accessdate=}}</ref>
It can be associated with:
*[[carcinoid]]
** [[Carinoid]] tumors can synthesis different types of amine and peptides, like serotonin, 5-hydroxytryptophan, ACTH, substance P, motilin, met-enkephalin, P-endorphin, neurotensin, gastrin, and somatostatin, but the agent which responsible for mesenteric vascular ischemia. Many of these substances have action on smooth muscles like substance P, motilin, and neurotensin which might have a role in the development of vascular elastosis.<ref name="urlwww.ncbi.nlm.nih.gov">{{cite web |url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434212/pdf/gut00218-0151.pdf |title=www.ncbi.nlm.nih.gov |format= |work= |accessdate=}}</ref>
** Midgut carcinoids are known to be more endocrinologically active than those arising from the hindgut, which may be the cause of the fact that elastic vascular sclerosis has not been found in the latter <ref name="urlwww.ncbi.nlm.nih.gov">{{cite web |url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434212/pdf/gut00218-0151.pdf |title=www.ncbi.nlm.nih.gov |format= |work= |accessdate=}}</ref>
*[[aortic coarctation]]
*[[antiphospholipid syndrome]]


==References==
==References==

Revision as of 01:03, 16 July 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Abdominal angina is an unusual cause of intermittent abdominal pain. Arterial vascular insufficiency is the cause of abdominal angina.The term angina is used because the pain develops only after eating, due to diminshed arterial supply that's needed to meet the increased demands to support digestion [1]. It's due to reduced mesenteric blood flow, reduced oxygen content of red blood cells distributed via the mesenteric arterial circulation, or mesenteric venous stasis, any of which can lead to tissue hypoxia and ischemic injury[1]

Pathophysiology

  • The pathophysiology is similar to that seen in angina pectoris and intermittent claudication.
  • Abdominal angina occurs due to narrowing of the mesenteric vessels that causes decreased blood flow.[2]
  • Atherosclerotic vascular disease at ostia of the mesenteric vessels is the most common cause of abdominal angina . Superior mesenteric artery occlusion is often found in patients presenting symptomatic occlusive mesenteric ischemia. Patients with abdominal angina are unable to increase flow in the mesenteric vessels in response to eating that's why they develop postprandial pain.[2]

References

  1. 1.0 1.1 "www.sciencedirect.com".
  2. 2.0 2.1 "Abdominal Angina - StatPearls - NCBI Bookshelf".