11β-hydroxylase deficiency other diagnostic studies: Difference between revisions

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:*Poorly defined zone borders
:*Poorly defined zone borders
:*Intermingling of the [[chromaffin]] and cortical cells
:*Intermingling of the [[chromaffin]] and cortical cells
* [[Amniotic fluid]] 11-deoxycortisol and oligonucleotide hybridization of deoxyribonucleic acid (DNA) obtained from chorionic villus biopsies.
* [[Amniotic fluid]] 11-deoxycortisol and oligonucleotide hybridization of deoxyribonucleic acid (DNA) obtained from chorionic villus biopsies
* [[DNA]] analysis
* [[DNA]] analysis



Revision as of 17:05, 9 February 2016

Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Immunohistochemical staining of the adrenal gland may be used for the diagnosis of congenital adrenal hyperplasia due to 11β-hydroxylase deficiency and it demonstrates hyperplasia, poorly defined zonation, and intermingling of the chromaffin and cortical cells.[1]

Other Diagnostic Studies

  • Immunohistochemical staining of the adrenal gland may be used in patients with classic 11β-hydroxylase deficiency and it demonstrates:[1]
  • Amniotic fluid 11-deoxycortisol and oligonucleotide hybridization of deoxyribonucleic acid (DNA) obtained from chorionic villus biopsies
  • DNA analysis

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