]> 2026-07-31T12:14:32+00:00 WBR1107 0 en Methylene blue Methylene blue reverses methemoglobinemia. Thiosulfate Thiosulfate reverses methomglobinemia in cases of cyanide poisoning. However, in this case dapsone pharmacotherapy was responsible for this patient’s methomglobinemia. N-acetylcysteine N-acetylcysteine reverses the toxicity of acetaminophen overdose. Naloxone Naloxone reverses the effects of opiate overdose. Vitamin C Vitamin C can be effective in treating methemoglobinemia, but it is considered an ancillary therapy. Pharmacology A 35-year-old man with HIV and documented trimethoprim-sulfamethoxazole allergy is placed on dapsone for pneumocystis prophylaxis when his CD4 count dropped below 200/mm3. Three weeks later, the patient presents to the emergency department with a 12-hour history of dyspnea, headache, dizziness, and blue discoloration of the lips and extremities. Pulse oximetry reveals an oxygen saturation of 82% on room air. When blood is drawn for arterial blood gas measurement, the nurse notices that it has a chocolate-brown color. Which of the following would be the most effective pharmacotherapy to manage this patient's condition? A Pulmonology 2020-10-28T02:37:53Z 2459150.6096412 WBR1107