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	<owl:Ontology rdf:about="https://www.wikidoc.org/index.php/Special:ExportRDF/WBR0961">
		<swivt:creationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2026-07-31T07:52:20+00:00</swivt:creationDate>
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		<rdfs:label>WBR0961</rdfs:label>
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		<swivt:page rdf:resource="https://www.wikidoc.org/index.php/WBR0961"/>
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		<swivt:wikiPageContentLanguage rdf:datatype="http://www.w3.org/2001/XMLSchema#string">en</swivt:wikiPageContentLanguage>
		<property:AnswerA rdf:datatype="http://www.w3.org/2001/XMLSchema#string">I.V platelet transfusion</property:AnswerA>
		<property:AnswerAExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">''' Incorrect ''' : There is no quantitative platelet loss in this patient that requires platelet transfusion.</property:AnswerAExp>
		<property:AnswerB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">I.V desmopressin</property:AnswerB>
		<property:AnswerC rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Von Willebrand factor transfusion</property:AnswerC>
		<property:AnswerCExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">''' Incorrect ''' : Patients with type 3 VWD, those with more severe type 1, and those with types 2A, 2B, and 2M disease often require replacement therapy with VWF, particularly in more serious bleeding situations when other measures have failed, or in settings when more prolonged treatment is required.</property:AnswerCExp>
		<property:AnswerD rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Cryoprecipitate infusion</property:AnswerD>
		<property:AnswerE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Proceed with the invasive procedure</property:AnswerE>
		<property:AnswerEExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">''' Incorrect ''' : This patient has VWF deficiency which has to be corrected with desopressin or VWF supplement before proceeding with any surgery.</property:AnswerEExp>
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		<property:ExamType rdf:resource="&wiki;USMLE_Step_3"/>
		<property:MainCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Emergency Room</property:MainCategory>
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		<property:Prompt rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A 30 year old female comes to the emergency department with an episode of bloody vomiting.  She was in her usual state this morning but suddenly developed these symptoms.  She had similar episodes thrice over the past one year, but never consulted a doctor.  She is a known hypertensive on regular medications.  Her past history is otherwise insignificant and her family history is positive for similar episodes in her brother.  Her menstrual cycles are normal.  She sexually active and uses contraceptives.  Her vitals are temperature: 36.7 C, blood pressure: 140/80 mmHg, pulse: 80/min and respiration: 15/min.  All system examinations are normal.  The patient is treated symptomatically and you plan to do a upper GI endoscopy. Her laboratory values are as follows : 

Hb : 13 g/dl
RBC’s : 2.5 million/cmm
WBC’s : 6000/cmm
Platelets : 250,000/cmm
Neutrophils : 60 %
Lymphocytes : 32 %
MCV : 85 fl
ESR : 15mm/hr
PT : 13 sec (N 11-15 sec)
APTT : 45 sec (N 25-40 sec)
BT : 18 min (N 2-7 min)
Serum creatinine : 1.2 mg/dl
Serum calcium : 9 g/dl

Which of the following is the best next step in the management of the patient?</property:Prompt>
		<property:RightAnswer rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A</property:RightAnswer>
		<property:SubCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hematology</property:SubCategory>
		<property:WBRKeyword rdf:resource="&wiki;Von_Willebrand_disease"/>
		<swivt:wikiPageModificationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-10-28T02:12:06Z</swivt:wikiPageModificationDate>
		<property:Modification_date-23aux rdf:datatype="http://www.w3.org/2001/XMLSchema#double">2459150.5917361</property:Modification_date-23aux>
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