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	<owl:Ontology rdf:about="https://www.wikidoc.org/index.php/Special:ExportRDF/WBR0829">
		<swivt:creationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2026-07-31T07:52:02+00:00</swivt:creationDate>
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		<rdfs:label>WBR0829</rdfs:label>
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		<property:AnswerA rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Continuous infusion of intravenous regular insulin and isotonic 0.9% normal saline</property:AnswerA>
		<property:AnswerAExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">'''Incorrect'''-Since the patient’s serum potassium has gone below 5.3 mEq/L, potassium should be added to the continuous infusion of intravenous regular insulin and isotonic 0.9% normal saline.</property:AnswerAExp>
		<property:AnswerB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Continuous infusion of intravenous regular insulin and hypertonic D5 normal saline</property:AnswerB>
		<property:AnswerBExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">'''Incorrect'''-Hypertonic D5 normal saline should replace the isotonic normal saline only when blood glucose falls below 200 mg/dL.</property:AnswerBExp>
		<property:AnswerC rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Continuous infusion of intravenous regular insulin, hypertonic D5 normal saline and potassium</property:AnswerC>
		<property:AnswerCExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">'''Incorrect'''-Hypertonic D5 normal saline should replace the isotonic normal saline only when blood glucose falls below 200 mg/dL.</property:AnswerCExp>
		<property:AnswerD rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Continuous infusion of intravenous regular insulin, isotonic 0.9% normal saline and potassium</property:AnswerD>
		<property:AnswerDExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">'''Correct'''-The first line of management of diabetic ketoacidosis (DKA) is starting the patient on a continuous infusion of intravenous regular insulin and isotonic 0.9% normal saline.  Potassium is supplemented when serum potassium falls below 5.3 mEq/L.</property:AnswerDExp>
		<property:AnswerE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Continuous infusion of intravenous regular insulin, isotonic 0.9% normal saline, potassium and sodium bicarbonate</property:AnswerE>
		<property:AnswerEExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">'''Incorrect'''-Sodium bicarbonate can be administered only when acidosis (&lt;7) is accompanied by a severe (&lt;5 mEq/L) fall in serum bicarbonate level and life threatening hyperkalemia.  Otherwise, sodium bicarbonate infusion can lead to neurological deterioration, slowing of the rate of recovery of ketosis and post treatment alkalosis.</property:AnswerEExp>
		<property:Approved rdf:resource="&wiki;Yes"/>
		<property:ExamType rdf:resource="&wiki;USMLE_Step_3"/>
		<property:MainCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Inpatient Facilities</property:MainCategory>
		<property:MainCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Emergency Room</property:MainCategory>
		<property:PageAuthor rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Vendhan Ramanujam</property:PageAuthor>
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		<property:Prompt rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A 28 year old African-American male presented to the emergency department with complaints of lethargy and vomiting for the past one day.  He is a known type 1 diabetes mellitus patient.  He had a gastrointestinal disturbance before two days following which he restricted his food intake and skipped his insulin doses.  He also played soccer with his friends last evening. Physical examination revealed a confused, dehydrated, tachypneic male with vital signs like heart rate of 120 beats/min, blood pressure of 98/58 mmHg, respiratory rate of 35/minute and oral temperature of 37.2 C.  A rapid finger glucose test revealed plasma glucose of 638 mg/dL, thus confirming diabetic ketoacidosis.  He was started on 0.9% normal saline while waiting for the following laboratory tests&lt;br&gt;
&lt;br&gt;
Serum sodium:       130 mEq/L&lt;br&gt;
Serum potassium:   5.2 mEq/L&lt;br&gt;
Serum chloride:       87 mEq/L&lt;br&gt;
Serum bicarbonate: 12 mEq/L&lt;br&gt;
Serum BUN:            32 mg/dL&lt;br&gt;
Serum creatinine:    1.5 mg/dL&lt;br&gt;
Blood glucose:         700 mg/dL&lt;br&gt;
Blood pH:                 7.08&lt;br&gt;
PaCO2:                    25 mmHg&lt;br&gt;
&lt;br&gt;
Urinary Ketones turned out to be positive.  Meanwhile he was transferred to the intensive care unit.  What is the next best step in line of management of this patient?</property:Prompt>
		<property:RightAnswer rdf:datatype="http://www.w3.org/2001/XMLSchema#string">D</property:RightAnswer>
		<property:SubCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Endocrine</property:SubCategory>
		<property:SubCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Electrolytes</property:SubCategory>
		<property:WBRKeyword rdf:resource="&wiki;Diabetic_ketoacidosis"/>
		<swivt:wikiPageModificationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-10-28T01:48:54Z</swivt:wikiPageModificationDate>
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