]> 2026-07-31T07:49:27+00:00 WBR0806 0 en Stomach The stomach is lined by gastric glands. Duodenum The duodenum is lined by villi and microvilli with the characteristic finding of Brunner glands. Ileum The ileum also contains villi and microvilli with the absence of Brunner glands. Colon The colon is characterized by the presence of crypts and goblet cells with the absence of villi. Esophagus The esophagus is characterized by the presence of nonkeratinized stratified squamous epithelium, as shown in the image above. Different parts of the GI tract are unique for the presence of different histological aspects that correspond with the function of every part. The histological appearance of esophagus is characterized by nonkeratinized stratified squamous epithelium as shown in the image above. In contrast, the stomach is lined by gastric glands. Generally, the duodenum, jejunum, and ileum have similar histological appearance but each has a unique features that differentiate them from each other. They contain villi and microvilli that increase the absorptive surface of the small intestine, crypts of Lieberkuhn, and plicae circulares. The hallmark of the duodenum is the presence of Brunner's glands. Finally, the colon contains crypts and abundant goblet cells but no villi.<br/> '''Educational Objective:''' The histological appearance of the esophagus is characterized by nonkeratinized stratified squamous epithelium.<br/> '''References:''' Kumar V, Abbas AK, Fausto N et al. Robbins and Cotran Pathologic Basis of Disease, Professional Edition, Expert Consult - Online. Elsevier Health Sciences; 2009. Histology E Gastrointestinal 2020-10-28T01:45:47Z 2459150.5734607 WBR0806