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	<owl:Ontology rdf:about="https://www.wikidoc.org/index.php/Special:ExportRDF/WBR0692">
		<swivt:creationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2026-07-31T10:04:31+00:00</swivt:creationDate>
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		<rdf:type rdf:resource="https://www.wikidoc.org/index.php/Special:URIResolver/Category-3AWBRQuestion"/>
		<rdf:type rdf:resource="https://www.wikidoc.org/index.php/Special:URIResolver/Category-3APages_using_duplicate_arguments_in_template_calls"/>
		<rdfs:label>WBR0692</rdfs:label>
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		<property:AnswerA rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Radiation induced fibrosis</property:AnswerA>
		<property:AnswerAExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Radiation induced fibrosis presents as shortness of breath and persists up to 6-24 months after treatment.  It is unlikely that dyspnoea because of radiation induced fibrosis presents 20 years after the treatment.</property:AnswerAExp>
		<property:AnswerB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pneumonia</property:AnswerB>
		<property:AnswerBExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pneumonia can occur during or after the treatment because of immunosuppression caused by chemotherapy, however, it is unlikely for pneumonia to occur as a late complication of cancer treatment.  Pulmonary function tests can also be affected because of radiation and chemotherapy, but recovery usually occurs within 3 years.</property:AnswerBExp>
		<property:AnswerC rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Leukemia</property:AnswerC>
		<property:AnswerCExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Leukemia is one the common secondary malignancies that occur because of cancer treatment.   Peak incidence of leukemia occurs up to 10 years after the treatment.</property:AnswerCExp>
		<property:AnswerD rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Breast cancer</property:AnswerD>
		<property:AnswerDExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Breast cancer and lung cancer are the most common solid tumors that occur after radiation and chemotherapy.   They usually present 15-20 years after the treatment of Hodgkin’s disease with radiation and chemotherapy.</property:AnswerDExp>
		<property:AnswerE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Fatigue</property:AnswerE>
		<property:AnswerEExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Fatigue due to cancer treatment usually lasts for 6 months or longer.  It is highly unlikely that fatigue as a result of cancer treatment presents 20 years after cancer treatment.</property:AnswerEExp>
		<property:Approved rdf:resource="&wiki;No"/>
		<property:ExamType rdf:resource="&wiki;USMLE_Step_2_CK"/>
		<property:Explanation rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hodgkin’s disease is a curable malignancy, however, patients are at an increased risk of developing secondary malignancies such as solid tumours, leukaemia and non Hodgkin’s lymphoma even after 20 years of follow up.  Lung and breast cancers are the most common among solid tumors.&lt;br&gt;
Other late complications of radiation and chemotherapy treatment for Hodgkin’s disease are cardiac involvement and hypothyroidism.&lt;br&gt;&lt;br/&gt;
'''Educational Objective:''' &lt;br/&gt;
'''References:'''</property:Explanation>
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		<property:Prompt rdf:datatype="http://www.w3.org/2001/XMLSchema#string">54 year old female comes with complaints of cough from 2 weeks with fever and shortness of breath.  She has no other significant complaints other than joint pains for which she takes over the counter analgesics.  Her past medical history is significant for hodgkin’s disease, which was treated with radiation and chemotherapy 20 years ago.  Which of the following adverse effects are most likely to present now as a result of hodgkin’s disease treatment?</property:Prompt>
		<property:RightAnswer rdf:datatype="http://www.w3.org/2001/XMLSchema#string">D</property:RightAnswer>
		<property:SubCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hematology</property:SubCategory>
		<property:SubCategory rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Oncology</property:SubCategory>
		<property:WBRKeyword rdf:resource="&wiki;Hodgkin-27s_lymphoma"/>
		<property:WBRKeyword rdf:resource="&wiki;Secondary_neoplasm"/>
		<swivt:wikiPageModificationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-10-28T01:25:47Z</swivt:wikiPageModificationDate>
		<property:Modification_date-23aux rdf:datatype="http://www.w3.org/2001/XMLSchema#double">2459150.5595718</property:Modification_date-23aux>
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