]> 2026-07-31T07:51:15+00:00 WBR0638 0 en Collagen type 1 Collagen type 1 is the most important component of a healed scarred wound. It is formed in the remodeling phase of wound healing and it replaces collagen type 3 to give the scar better strength. Collagen type 2 Collagen type 2 is seen in cartilagenous structures like the distal ends of long bones, the vitreous body, and the nucleus pulposus but not in healing wounds. Collagen type 3 Collagen type 3 is important in granulation tissue during wound healing. It is replaced by collagen type 1 seen in healed scars. Collagen type 3 would be more abundant in the larger unhealed ulcer in our patient. Collagen type 4 Collagen type 4 is also known as basal membrane or basal lamina. It is needed for tissue integrity and cellular attachments. It is not more abundant in healed wounds. Elastin Elastin content is a property of tissue type and is not usually increased in scar tissue. Biochemistry Pathology A 48-year-old diabetic patient presents to the wound care clinic for a new 4 cm right foot ulcer he recently discovered while showering. The patient has a history of poorly controlled diabetes and 2 previous ulcers on his left foot one of which led to a toe amputation. While examining the patient, you note a large ulcer, approximately 1 cm deep, with a bright red base and a clean border. You also notice a smaller 2 cm ulcer that is almost completely healed. Compared to the larger ulcer which of the following is more abundant in the smaller ulcer? A Dermatology General Principles 2020-10-28T01:16:47Z 2459150.5533218 WBR0638