]> 2026-07-31T12:14:24+00:00 WBR0635 0 en Linezolid Linezolid is a first line therapy for CA-MRSA. There are no contraindications for its use in our patient. Daptomycin Daptomycin is contraindicated in CA-MRSA pneumonia since it is inactivated by the pulmonary surfactant. Vancomycin Vancomycin is a first line therapy for CA-MRSA. There are no contraindications for its use in our patient. Ceftaroline Ceftaroline is a new generation cephalosporin with broad spectrum and activity against MRSA. Recent clinical trials have shown that Ceftaroline is a good option for MRSA pneumonia, although its use is still not recommended by international guidelines. Clindamycin Clindamycin is a second line therapy for CA-MRSA pneumonia in patients that cannot for any reason receive vancomycin or linezolid. Microbiology Pharmacology A 68-year-old woman with history of chronic obstructive pulmonary disease (COPD) presents for 2 days of purulent productive cough with fever and chills noted in the last 3 hours. You obtain a chest x-ray that confirms your suspicion of pneumonia and admit the patient for intravenous antibiotics. Despite empiric therapy, the patient continues to worsen over the next few days. Sputum cultures obtained on admission grow gram-positive cocci in clusters that show resistance to oxacillin. Which of the following antibiotics is contraindicated in this patient? B Infectious Disease 2020-10-28T01:15:59Z 2459150.5527662 WBR0635