]> 2026-07-31T07:51:26+00:00 WBR0600 0 en Lichen sclerosus Lichen simplex chronicus Lichen planus Lichen planus is a chronic inflammatory disease that affects the skin and the mucous membrane. It is associated with chronic hepatitis C infection. It may affect the skin, oral cavity, genitalia, scalp, nails, or esophagus. The clinical features of cutaneous lichen planus are pruritus, purple, polygonal papules, and plaques (6 Ps) with Wickham striae (white striations). Diagnosis is by biopsy that demonstrates sawtooth lymphocytic infiltration at the dermal-epidermal junction. First line therapy is topical corticosteroids. Contact dermatitis Contact dermatitis is an chemical-induced inflammation of the skin that directly damage the skin. It is commonly caused by bee sting, nickel, or rubber gloves. Clinical presentation, which is usually preceded by the exposure to the irritant, involves the appearance of pruritic papules and vesicles on an erythematous base. The lesion may become either hyper or hypopigmented with time. Topical corticosteroids are the mainstay of treatment. Vitiligo Vitiligo is an autoimmune disorder characterized by the presence of auto-antibodies against the melanocyte cells of the skin. It manifests with loss of pigment that results in irregular pale patches of skin. Treatment is with topical corticosteroids and phototherapy using PUVA (Psoralen and ultraviolet A). Pathology B Dermatology 2020-10-28T01:08:37Z 2459150.5476505 WBR0600