]> 2026-07-31T07:51:56+00:00 WBR0520 0 en Factor VIII deficiency Disseminated intravascular coagulation Blood transfusion reaction '''Incorrect'''-Blood transfusion reactions can cause diffuse loss of clot integrity and a sudden diffuse bleeding during an operation may be the only evidence of an intraoperative transfusion reaction. In the postoperative period, transfusion reactions usually present as unexplained fever, apprehension, and headache, which all are difficult to interpret in the early postoperative period. A bleeding blood vessel in the surgical field '''Correct'''-Whenever significant bleeding happens in the early postoperative period with normal coagulation profile, the presumption should always be towards an error in the surgical control of blood vessels in the operative field. Hematologic disorders that are not apparent during the long operation are most unlikely to surface as problems postoperatively. Acquired von Willebrand disease Whenever significant bleeding happens in the early postoperative period, the presumption should always be towards an error in the surgical control of blood vessels in the operative field. Hematologic disorders that are not apparent during the long operation are most unlikely to surface as problems postoperatively. The low platelet count here could be due to post transfusion hemodilution. '''Educational Objective:''' Whenever significant bleeding happens in the early postoperative period with normal coagulation profile, the presumption should always be towards an error in the surgical control of blood vessels in the operative field. Hematologic disorders that are not apparent during the long operation are most unlikely to surface as problems postoperatively.<br/> '''Educational Objective:''' <br/> '''References:''' Inpatient Facilities Vendhan Ramanujam A 55 year old man underwent an abdominoperineal resection for a stage 1 rectal cancer. During the surgery, he received 3 units of packed red blood cells. After successful resection, the patient was sent to the intensive care unit for close monitoring. Five hours later, in the intensive care unit, he started bleeding heavily from his perineal wound. Emergency coagulation studies were ordered and it revealed the following results<br> Prothrombin time: 12 seconds<br> Partial thromboplastin time: 64 seconds<br> Bleeding time: 3 minutes<br> Fibrin degradation products: 3 mg/L <br> Serum fibrinogen: 160 mg/dL<br> Platelet count: 80,000/μL<br> <br> The most likely cause of bleeding in this patient is D Gastrointestinal Hematology Surgery 2020-10-28T00:50:44Z 2459150.5352315 WBR0520