]> 2026-07-31T07:53:15+00:00 WBR0473 0 en ''Streptococcus bovis'' ''S. bovis'' infection is often associated with colon cancer. ''Staphylococcus saprophyticus'' ''S. saprophyticus'' is a common cause of urinary tract infections in sexually active women. It is not a common cause of infections of implanted prosthetic material. All staphylococcal organisms are non-motile. To distinguish, ''S. saprophyticus'' is novobiocin-resistant, while ''S. epidermidis'' is novobiocin-sensitive. ''Neisseria gonorrhea'' ''N. gonorrhea'' is a sexually transmitted infection that can cause infectious arthritis. ''Pseudomonas aeruginosa'' ''P. aeruginosa'' may be an infectious cause of a complicated total knee replacement. However, ''P. aeroginosa'' is a motile organism. ''Staphylococcus epidermidis'' ''S. epidermidis'' is a gram-positive, catalase-positive, coagulase-negative non-motile organism that is commonly associated with infections following prosthetic implant due to its ability to form antibiotic-resistant biofilms. Infection of an implanted foreign prosthetic material is a relatively common complication that is often caused by ''Staphylococcus epidermidis'' infection. ''S. epidermidis'' is a gram-positive coagulase-negative non-motile organism that causes biofilms that grow on surgical implants or catheters. ''S. epidermidis'' is a catalase-positive, coagulase-negative, facultative anaerobe. It has a weak positive reaction to nitrate reduction test. Also, ''S. epidermidis'' is sensitive to novobiocin. To distinguish ''S. epidermidis'' from other staphylococcal organisms, ''S. aureus'' is coagulase-positive and ''S. saprophyticus'' is novobiocin-resistant. An important virulence factor of ''S. epidermidis'' is its surface proteins that can result in the formation of antibiotic-resistant biofilms on plastic devices. Administration of antibiotics and surgical removal of the implanted device are generally both required for appropriate treatment of prosthetic material infection. Of note, ''S. epidermidis'' is part of the normal skin and mucosal microflora and often contaminates blood or urine cultures.<br/> '''Educational Objective:''' ''S. epidermidis'' is a gram-positive, catalase-positive, coagulase-negative non-motile organism that is commonly associated with infections following prosthetic implant due to its ability to form antibiotic-resistant biofilms.<br/> '''References:''' First Aid 2014 page 130 Microbiology A 67-year-old woman presents to the emergency department for unremitting high-grade fever and left leg pain. The patient explains that she had a left total knee replacement 5 months ago. The patient is admitted and blood cultures are withdrawn. The next day, blood cultures grow a non-motile organism. Which of the following pathogens is most likely responsible for the patient's condition? E Cardiology 2020-10-28T00:41:44Z 2459150.5289815 WBR0473