]> 2026-07-31T11:50:36+00:00 WBR0434 0 en Inhibition of heme polymerase activity Inhibition of dihydrofolate reductase activity Free radical toxicity of organism’s DNA Blockade of peptide bond formation at the 50S ribosomal subunit Inhibition of DNA polymerase activity Microbiology A 28-year-old HIV-positive woman is brought to the emergency department (ED) with an episode of tonic-clonic seizure. The patient's family reports that the patient has recently lost weight and has been having complaints of high-grade fever and headaches for the past few days. The patient has been non-compliant with her anti-retroviral therapy for the past few weeks. Laboratory work-up in the ED is remarkable for CD4 count=80 cells/µL. Head computed tomography (CT) scan demonstrates multiple ring-enhancing lesions in the frontal lobes. The patient is administered empiric pharmacotherapy and is admitted to the hospital. What is the mechanism of action of the drug administered to this patient to treat her condition? B Neurology 2020-10-28T00:32:48Z 2459150.5227778 WBR0434