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	<owl:Ontology rdf:about="https://www.wikidoc.org/index.php/Special:ExportRDF/WBR0312">
		<swivt:creationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2026-07-31T04:22:46+00:00</swivt:creationDate>
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	<swivt:Subject rdf:about="https://www.wikidoc.org/index.php/Special:URIResolver/WBR0312">
		<rdf:type rdf:resource="https://www.wikidoc.org/index.php/Special:URIResolver/Category-3AWBRQuestion"/>
		<rdfs:label>WBR0312</rdfs:label>
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		<swivt:page rdf:resource="https://www.wikidoc.org/index.php/WBR0312"/>
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		<property:AnswerA rdf:datatype="http://www.w3.org/2001/XMLSchema#string">50 to 60 years</property:AnswerA>
		<property:AnswerAExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sixty years is the median lifespan of patients with Down Syndrome. However, many patients with Down syndrome are affected by Alzheimer’s disease between the ages of 40 and 50.</property:AnswerAExp>
		<property:AnswerB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">10 to 15 years</property:AnswerB>
		<property:AnswerBExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Ten years is the median lifespan of patients with progerioid syndromes such as Hutchinson-Gilford progeria.</property:AnswerBExp>
		<property:AnswerC rdf:datatype="http://www.w3.org/2001/XMLSchema#string">1 to 2 years</property:AnswerC>
		<property:AnswerCExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">One year is the median lifespan of patients with Patau syndrome. Patau syndrome is caused by an extra copy of chromosome 13 (trisomy 13).</property:AnswerCExp>
		<property:AnswerD rdf:datatype="http://www.w3.org/2001/XMLSchema#string">1 to 2 weeks</property:AnswerD>
		<property:AnswerDExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Among those who survive, patients with Edwards' syndrome have a median lifespan of approximately 1 week (5 to 15 days).</property:AnswerDExp>
		<property:AnswerE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">1 to 2 days</property:AnswerE>
		<property:AnswerEExp rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The median lifespan of anencephaly is on the order of approximately one day.</property:AnswerEExp>
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		<property:Explanation rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Edwards' syndrome is a chromosomal abnormality caused by the presence of all or part of an extra 18th chromosome (trisomy 18). Approximately 80% of patients with Edward's syndrome are female. The majority of fetuses with the syndrome die before birth; those who survive have a median lifespan of approximately 1 to 2 weeks. Fewer than 10% of patients with Edwards' syndrome live beyond 1 year. The physical characteristics of Edwards' syndrome include the following:
* Intellectual disability
* Clenched fingers (shown in the picture above)
* Micrognathia 
* Microcephaly
* Prominent occiput
* Low-set, dysmorphic ears
* Cleft lip and/or palate
* Webbing of the toes
* Rocker bottom feet&lt;br/&gt;
'''Educational Objective:''' Edwards' syndrome is a chromosomal abnormality of chromosome 18 (trisomy 18) with severe abnormal facies and symptoms. The majority of patients with Edwards' syndrome die before birth. Among those who survive, the median lifespan of live births is approximately 1 to 2 weeks.&lt;br/&gt;
'''References:''' Image: Attribution to "Overlapping fingers.JPG" uploaded by user:Bobjgalindo licensed under the GNU Free Documentation license. commons.wikimedia.org. Retrieved Jan 9 2015.&lt;br&gt;
First Aid 2014 page 90</property:Explanation>
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		<property:RightAnswer rdf:datatype="http://www.w3.org/2001/XMLSchema#string">D</property:RightAnswer>
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		<property:WBRKeyword rdf:resource="&wiki;Chromosome"/>
		<property:WBRKeyword rdf:resource="&wiki;Edwards_syndrome"/>
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		<property:WBRKeyword rdf:resource="&wiki;Chromosomal_Abnormality"/>
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		<property:WBRKeyword rdf:resource="&wiki;Median_life_expectancy"/>
		<swivt:wikiPageModificationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-10-28T00:09:37Z</swivt:wikiPageModificationDate>
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