]> 2026-07-31T07:28:11+00:00 WBR0119 0 en 46,XXY Patients with Klinefelter's syndrome have an additionally X chromosome. The total number of chromosomes is thus 47, not 46. 44,XXY Patients with Klinefelter's syndrome have an additional X chromosome. The total number of chromosomes is thus 47, not 44. Denoting a karyotype includes the ''total'' number of chromosomes, including autosomes and sex chromosomes, followed by the identity of sex chromosomes. 45,XO 46,XX/XY This karyotype refers to a rare mosaic chromosomal abnormality which causes some cells in the body to have XX chromosomes and some to have XY chromosomes. This karyotype causes intersex conditions. 47,XXY Genetics A young couple presents to the physician's office for infertility after 18 months of failed attempts at conception despite appropriate measures. Upon further questioning, the woman had previously conceived and given birth to a healthy child in a separate relationship. The man is currently being evaluated for infertility. On physical examination, the patient is found to have low muscle mass, gynecomastia, and small testes. Laboratory studies reveal markedly elevated LH and FSH. The physician orders chromosomal karyotyping to confirm the diagnosis. Which of the following is the most likely karyotype of this patient? E Reproductive 2020-10-27T23:24:30Z 2459150.4753472 WBR0119