]> 2026-07-31T09:38:58+00:00 WBR0072 0 en Colchicine Estramustine Irinotecan Ixabepilone Vincristine The vinca alkaloids, in common with other drugs such as colchicine, podophyllotoxin, the taxanes, and the epothilones, block cells in mitosis. Their mechanism of action is to bind specifically to beta-tubulin and to block its polymerization with alpha-tubulin into microtubules. Pharmacology Anonymous (Reviewed by Will Gibson and Yazan Daaboul) A new chemotherapeutic drug of unclear mechanism is under investigation. After treatment with the drug, hamster ovary cells are found to be arrested in metaphase. Further studies show that the drug and paclitaxel both bind to beta-tubulins and promote stabilization of microtubules. Which of the following drugs is most likely to have the same mode of action? D Oncology 2020-10-27T23:14:39Z 2459150.4685069 WBR0072