Dorzolamide

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Dorzolamide
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gerald Chi

Disclaimer

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Overview

Dorzolamide is a carbonic anhydrase inhibitor that is FDA approved for the {{{indicationType}}} of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Common adverse reactions include taste alteration, hypersensitivity reaction, punctate keratitis, and visual discomfort.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Elevated Intraocular Pressure or Open-Angle Glaucoma
  • Dosing Information
  • One drop in the affected eye(s) three times daily

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Dorzolamide in adult patients.

Non–Guideline-Supported Use

Prophylaxis of Ocular Hypertension
  • Dosing Information
  • One drop 1–4 hours after anterior segment laser surgery

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

Elevated Intraocular Pressure or Open-Angle Glaucoma
  • Dosing Information
  • One drop in the affected eye(s) three times daily

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Dorzolamide in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Dorzolamide in pediatric patients.

Contraindications

  • Condition1

Warnings

Description

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Dorzolamide in the drug label.

Central Nervous System
Cardiovascular
Respiratory
Gastrointestinal
Hypersensitivity
Miscellaneous

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Dorzolamide in the drug label.

Central Nervous System
Cardiovascular
Respiratory
Gastrointestinal
Hypersensitivity
Miscellaneous

Drug Interactions

  • Drug
  • Description

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • Pregnancy Category


Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Dorzolamide in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Dorzolamide during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Dorzolamide with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Dorzolamide with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Dorzolamide with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Dorzolamide with respect to specific gender populations.

Race

There is no FDA guidance on the use of Dorzolamide with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Dorzolamide in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Dorzolamide in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Dorzolamide in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Dorzolamide in patients who are immunocompromised.

Administration and Monitoring

Administration

Oral

Intravenous

Monitoring

There is limited information regarding Monitoring of Dorzolamide in the drug label.

Condition1

Description

IV Compatibility

There is limited information regarding IV Compatibility of Dorzolamide in the drug label.

Overdosage

Acute Overdose

Signs and Symptoms

Description

Management

Description

Chronic Overdose

There is limited information regarding Chronic Overdose of Dorzolamide in the drug label.

Pharmacology

There is limited information regarding Dorzolamide Pharmacology in the drug label.

Mechanism of Action

There is limited information regarding Dorzolamide Mechanism of Action in the drug label.

Structure

There is limited information regarding Structure of Dorzolamide in the drug label.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Dorzolamide in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Dorzolamide in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Dorzolamide in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Dorzolamide in the drug label.

Condition1

Description

How Supplied

There is limited information regarding Dorzolamide How Supplied in the drug label.

Storage

There is limited information regarding Dorzolamide Storage in the drug label.

Images

Drug Images

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Package and Label Display Panel

{{#ask: Label Page::Dorzolamide |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Patient Counseling Information of Dorzolamide in the drug label.

Precautions with Alcohol

Alcohol-Dorzolamide interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

Trusopt Ocumeter[1]

Look-Alike Drug Names

N/A[2]

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. "DORZOLAMIDE HCL SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]".
  2. "http://www.ismp.org". External link in |title= (help)


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