Sandbox/23

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System Stage 1 (Localized) Stage 2 (Disseminated) Stage 3 (Persistent)
Skin Erythema migrans Secondary annular lesions Acrodermatitis chronica atrophicans
Malar rash Localized scleroderma-like lesions
Diffuse erythema or urticaria
Evanescent lesions
Lymphocytoma
Musculoskeletal Migratory arthralgia Prolonged arthritis attacks
Brief arthritis attacks Chronic arthritis
Myositis Peripheral enthesopathy
Osteomyelitis Periostitis or joint subluxations below acrodermatitis
Panniculitis
Neurologic Meningitis Chronic encephalomyelitis
Cranial neuritis or Bell's palsy Spastic parapareses
Motor or sensory radiculoneuritis Ataxic gait
Encephalitis Mental disorders
Mononeuritis multiplex Chronic axonal polyradiculopathy
Pseudotumor cerebri Dementia
Myelitis
Chorea
Cerebellar ataxia
Lymphatic Regional lymphadenopathy Regional or generalized lymphadenopathy
Splenomegaly
Heart Atrioventricular nodal block
Myopericarditis
Pancarditis
Eyes Conjunctivitis Keratitis
Iritis
Choroiditis
Retinal hemorrhage or detachment
Panophthalmitis
Liver Mild or recurrent hepatitis
Respiratory Nonexudative sore throat
Nonproductive cough
Adult respiratory distress syndrome
Kidney Microscopic hematuria or proteinuria
Genitourinary Orchitis
Constitutional systems Minor Severe malaise and fatigue Fatigue