WBR0529
| Author | [[PageAuthor::Rim Halaby, M.D. [1]]] |
|---|---|
| Exam Type | ExamType::USMLE Step 1 |
| Main Category | |
| Sub Category | |
| Prompt | [[Prompt::To study the effects of a newly developed drug, a researcher uses polarized microscopy to monitor the changes in living Pectinaria oocytes exposed to intermittent doses of this agent. Although most oocytes were not directly affected, those in active replication seemed to arrest at a certain point during mitosis with a significant reduction in the size of meiotic spindles, as measured by loss of birefringence under polarized light. The researcher also noticed that shortly after the exposure to the drug was eliminated, mitosis would resume and the spindles would regain birefringence. Which of the following drugs most likely has the same mechanism of action?]] |
| Answer A | AnswerA::Carboplatin |
| Answer A Explanation | AnswerAExp:: |
| Answer B | AnswerB::Amantadine |
| Answer B Explanation | AnswerBExp:: |
| Answer C | AnswerC::Griseofulvin |
| Answer C Explanation | AnswerCExp:: |
| Answer D | AnswerD::Etoposide |
| Answer D Explanation | AnswerDExp:: |
| Answer E | AnswerE::Caspofungin |
| Answer E Explanation | AnswerEExp:: |
| Right Answer | RightAnswer::C |
| Explanation | [[Explanation:: Educational Objective: |
| Approved | Approved::No |
| Keyword | WBRKeyword::Griseofulvin, WBRKeyword::microtubule, WBRKeyword::mitosis |
| Linked Question | Linked:: |
| Order in Linked Questions | LinkedOrder:: |