Cardiac amyloidosis nuclear cardiac scans

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]; Aarti Narayan, M.B.B.S [3]

Overview

Nuclear cardiac scans like MUGA and radionuclide ventriculography (RNV) are not used routinely early in the diagnosis of cardiac amyloidosis. However, when performed, these scans show increased uptake of technetium by the myocardium correlating well with the degree of involvement.

Nuclear Cardiac Scans

99mTechnetium-dicarboxypropane diphosphonate (99mTc-DPD) is an isotope available in Europe. Imaging with 99mTc-DPD is shown to help distinguish between AL and ATTR cardiac amyloidosis. [1]

References

  1. Perugini E, Guidalotti PL, Salvi F; et al. (2005). "Noninvasive etiologic diagnosis of cardiac amyloidosis using 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy". Journal of the American College of Cardiology. 46 (6): 1076–84. doi:10.1016/j.jacc.2005.05.073. PMID 16168294. Unknown parameter |month= ignored (help)


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