Fungal meningitis laboratory findings

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The General characteristic CSF Findings in Fungal Meningitis:

  • Mononuclear or lymphocytic pleocytosis
  • An elevated protein concentration
  • A decreased glucose concentration

Other CSF Findings and Tests Specific to Particular Fungi

CSF culture

Fungal stain and culture of CSF Biopsy and culture of skin, lung lesions Antibody detection in serum

India ink or fungal wet mount of CSF (budding yeast) Blood and urine cultures Antigen detection in CSF

Antibody detection in CSF and serum

Fungal stain and culture of CSF

Fungal stain and culture of large volumes of CSF Antigen detection in CSF, serum, and urine Antibody detection in serum, CSF

Antibody detection in CSF and serum; CSF culture[1]

  1. Koroshetz WJ. Chapter 382. Chronic and Recurrent Meningitis. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, eds. Harrison's Principles of Internal Medicine. 18th ed. New York: McGraw-Hill; 2012.