RAB11A

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RAB11A, member RAS oncogene family
File:PBB Protein RAB11A image.jpg
PDB rendering based on 1oiv.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols RAB11A ; MGC1490; YL8
External IDs Template:OMIM5 Template:MGI HomoloGene37903
RNA expression pattern
File:PBB GE RAB11A 200863 s at tn.png
File:PBB GE RAB11A 200864 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

RAB11A, member RAS oncogene family, also known as RAB11A, is a human gene.

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport.[1]

References

  1. "Entrez Gene: RAB11A RAB11A, member RAS oncogene family".

Further reading

  • Drivas GT, Shih A, Coutavas EE; et al. (1991). "Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3". Oncogene. 6 (1): 3–9. PMID 1704119.
  • Sakurada K, Uchida K, Yamaguchi K; et al. (1991). "Molecular cloning and characterization of a ras p21-like GTP-binding protein (24KG) from rat liver". Biochem. Biophys. Res. Commun. 177 (3): 1224–32. PMID 1711847.
  • Gromov PS, Celis JE, Hansen C; et al. (1998). "Human rab11a: transcription, chromosome mapping and effect on the expression levels of host GTP-binding proteins". FEBS Lett. 429 (3): 359–64. PMID 9662449.
  • Gromov P, Celis JE (1998). "Rab11a is modified in vivo by isoprenoid geranylgeranyl". Electrophoresis. 19 (10): 1803–7. doi:10.1002/elps.1150191043. PMID 9719562.
  • Zeng J, Ren M, Gravotta D; et al. (1999). "Identification of a putative effector protein for rab11 that participates in transferrin recycling". Proc. Natl. Acad. Sci. U.S.A. 96 (6): 2840–5. PMID 10077598.
  • Dumanchin C, Czech C, Campion D; et al. (1999). "Presenilins interact with Rab11, a small GTPase involved in the regulation of vesicular transport". Hum. Mol. Genet. 8 (7): 1263–9. PMID 10369872.
  • Mammoto A, Ohtsuka T, Hotta I; et al. (1999). "Rab11BP/Rabphilin-11, a downstream target of rab11 small G protein implicated in vesicle recycling". J. Biol. Chem. 274 (36): 25517–24. PMID 10464283.
  • Shisheva A, Chinni SR, DeMarco C (1999). "General role of GDP dissociation inhibitor 2 in membrane release of Rab proteins: modulations of its functional interactions by in vitro and in vivo structural modifications". Biochemistry. 38 (36): 11711–21. PMID 10512627.
  • Prekeris R, Klumperman J, Scheller RH (2001). "A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes". Mol. Cell. 6 (6): 1437–48. PMID 11163216.
  • Lapierre LA, Kumar R, Hales CM; et al. (2001). "Myosin vb is associated with plasma membrane recycling systems". Mol. Biol. Cell. 12 (6): 1843–57. PMID 11408590.
  • Prekeris R, Davies JM, Scheller RH (2001). "Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins". J. Biol. Chem. 276 (42): 38966–70. doi:10.1074/jbc.M106133200. PMID 11481332.
  • Hales CM, Griner R, Hobdy-Henderson KC; et al. (2001). "Identification and characterization of a family of Rab11-interacting proteins". J. Biol. Chem. 276 (42): 39067–75. doi:10.1074/jbc.M104831200. PMID 11495908.
  • Lindsay AJ, Hendrick AG, Cantalupo G; et al. (2002). "Rab coupling protein (RCP), a novel Rab4 and Rab11 effector protein". J. Biol. Chem. 277 (14): 12190–9. doi:10.1074/jbc.M108665200. PMID 11786538.
  • Lindsay AJ, McCaffrey MW (2002). "Rab11-FIP2 functions in transferrin recycling and associates with endosomal membranes via its COOH-terminal domain". J. Biol. Chem. 277 (30): 27193–9. doi:10.1074/jbc.M200757200. PMID 11994279.
  • Scales SJ, Hesser BA, Masuda ES, Scheller RH (2002). "Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly". J. Biol. Chem. 277 (31): 28271–9. doi:10.1074/jbc.M204929200. PMID 12145319.
  • Band AM, Ali H, Vartiainen MK; et al. (2002). "Endogenous plasma membrane t-SNARE syntaxin 4 is present in rab11 positive endosomal membranes and associates with cortical actin cytoskeleton". FEBS Lett. 531 (3): 513–9. PMID 12435603.
  • Wallace DM, Lindsay AJ, Hendrick AG, McCaffrey MW (2003). "Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells". Biochem. Biophys. Res. Commun. 299 (5): 770–9. PMID 12470645.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Roosterman D, Schmidlin F, Bunnett NW (2003). "Rab5a and rab11a mediate agonist-induced trafficking of protease-activated receptor 2". Am. J. Physiol., Cell Physiol. 284 (5): C1319–29. doi:10.1152/ajpcell.00540.2002. PMID 12540381.
  • Tani K, Shibata M, Kawase K; et al. (2003). "Mapping of functional domains of gamma-SNAP". J. Biol. Chem. 278 (15): 13531–8. doi:10.1074/jbc.M213205200. PMID 12554740.

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