Fipexide

Fipexide
Clinical data
ATC code	N06BX05 (WHO) ;
Identifiers
	IUPAC name 1-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-; 2-(4-chlorophenoxy)ethanone;
CAS Number	34161-24-5;
PubChem CID	3351;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C20H21ClN2O4
Molar mass	388.845 g/mol

Fipexide is a piperazine derivative drug invented in Italy in 1983.^[1]

It was used as a nootropic drug in France and Italy, mainly for the treatment of senile dementia,^[2] but is no longer in common use due to the occurrence of rare adverse drug reactions including fever^[3] and hepatitis. Fipexide is similar in action to other nootropic drugs such as piracetam and is structurally similar to another more well-known nootropic, centrophenoxine.

References

↑ Missale C, Pasinetti G, Govoni S, Spano PF, Trabucchi M. Fipexide: a new drug for the regulation of dopaminergic system at the macromolecular level. Bollettino Chimico Farmaceutico. 1983 Feb;122(2):79-85.
↑ Bompani R, Scali G. Fipexide, an effective cognition activator in the elderly: a placebo-controlled, double-blind clinical trial. Current Medical Research and Opinion. 1986;10(2):99-106.
↑ Guy C, Blay N, Rousset H, Fardeau V, Ollagnier M. Fever caused by fipexide. Evaluation of the national pharmacovigilance survey. Therapie. 1990 Sep-Oct;45(5):429-31.

Template:Psychostimulants, agents used for ADHD and nootropics Template:WikiDoc Sources

[1] Missale C, Pasinetti G, Govoni S, Spano PF, Trabucchi M. Fipexide: a new drug for the regulation of dopaminergic system at the macromolecular level. Bollettino Chimico Farmaceutico. 1983 Feb;122(2):79-85.

[2] Bompani R, Scali G. Fipexide, an effective cognition activator in the elderly: a placebo-controlled, double-blind clinical trial. Current Medical Research and Opinion. 1986;10(2):99-106.

[3] Guy C, Blay N, Rousset H, Fardeau V, Ollagnier M. Fever caused by fipexide. Evaluation of the national pharmacovigilance survey. Therapie. 1990 Sep-Oct;45(5):429-31.

[1]

[2]

[3]

Clinical data

ATC code	N06BX05 (WHO)
Identifiers
IUPAC name 1-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]- 2-(4-chlorophenoxy)ethanone
CAS Number	34161-24-5
PubChem CID	3351
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₀H₂₁ClN₂O₄
Molar mass	388.845 g/mol

Fipexide

References

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