Heparin mechanism of action

WikiDoc Resources for Heparin mechanism of action
Articles
Most recent articles on Heparin mechanism of action Most cited articles on Heparin mechanism of action Review articles on Heparin mechanism of action Articles on Heparin mechanism of action in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Heparin mechanism of action Images of Heparin mechanism of action Photos of Heparin mechanism of action Podcasts & MP3s on Heparin mechanism of action Videos on Heparin mechanism of action
Evidence Based Medicine
Cochrane Collaboration on Heparin mechanism of action Bandolier on Heparin mechanism of action TRIP on Heparin mechanism of action
Clinical Trials
Ongoing Trials on Heparin mechanism of action at Clinical Trials.gov Trial results on Heparin mechanism of action Clinical Trials on Heparin mechanism of action at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Heparin mechanism of action NICE Guidance on Heparin mechanism of action NHS PRODIGY Guidance FDA on Heparin mechanism of action CDC on Heparin mechanism of action
Books
Books on Heparin mechanism of action
News
Heparin mechanism of action in the news Be alerted to news on Heparin mechanism of action News trends on Heparin mechanism of action
Commentary
Blogs on Heparin mechanism of action
Definitions
Definitions of Heparin mechanism of action
Patient Resources / Community
Patient resources on Heparin mechanism of action Discussion groups on Heparin mechanism of action Patient Handouts on Heparin mechanism of action Directions to Hospitals Treating Heparin mechanism of action Risk calculators and risk factors for Heparin mechanism of action
Healthcare Provider Resources
Symptoms of Heparin mechanism of action Causes & Risk Factors for Heparin mechanism of action Diagnostic studies for Heparin mechanism of action Treatment of Heparin mechanism of action
Continuing Medical Education (CME)
CME Programs on Heparin mechanism of action
International
Heparin mechanism of action en Espanol Heparin mechanism of action en Francais
Business
Heparin mechanism of action in the Marketplace Patents on Heparin mechanism of action
Experimental / Informatics
List of terms related to Heparin mechanism of action

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Mechanism of action

• Heparin is an indirect thrombin inhibitor.

• It forms a complexes with antithrombin / AT III (predominantly) and other factors like factor Xa, factors XIIa, XIa, and IXa, that results in a conformational change in AT, converting antithrombin from a slow to a rapid inactivator of thrombin

• Antithrombin has two active sites:
  • Reactive center, Arg393-Ser394
  • Heparin binding sites