Patent foramen ovale and migraine
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [3]
Overview
Migraine headaches, particular those with an aura, have been associated with a patent foramen ovale.
Patent foramen ovale and migraine
A recent metanalysis that included 18 studies and comprised 2636 patients has found a low-grade association between migraines in patients with patent foramen ovale (PFO). However, the results of this study should be interpreted with cautions, as the individual studies included for the metanalysis were quite heterogeneous. There was some association seen in patients of migraine with aura {odds ratio of 3.21(95% CI 2.38–4.70) }but no relation existed for patients of migraine without aura