Idiopathic pulmonary fibrosis (patient information)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor-in-Chief: Alexandra M. Palmer

Overview

Idiopathic pulmonary fibrosis is scarring or thickening of the lungs without a known cause.

What are the symptoms of Idiopathic pulmonary fibrosis?

  • Chest pain (occasionally)
  • Cough (usually dry)
  • Decreased tolerance for activity
  • Shortness of breath during activity (this symptom lasts for months or years, and over time may also occur when at rest)

What causes Idiopathic pulmonary fibrosis?

No one knows what causes pulmonary fibrosis or why some people get it. It causes the lungs to become scarred and stiffened. This stiffening may make it increasingly difficult to breathe. In some people the disease gets worse quickly (over months to a few years), but other people have little worsening of the disease over time.

The condition is believed to result from an inflammatory response to an unknown substance. "Idiopathic" means no cause can be found. The disease occurs most often in people between 50 and 70 years old.

How do I know I have Idiopathic pulmonary fibrosis?

The health care provider will perform a physical exam and ask questions about your medical history. Your doctor will ask whether you have been exposed to asbestos and if you have been a smoker.

Patients with idiopathic pulmonary fibrosis have abnormal breath sounds called crackles. Patients with advanced disease may have blue-colored skin (cyanosis) around the mouth or in the fingernails due to low oxygen.

Examination of the fingers and toes may show abnormal enlargement of the fingernail bases (clubbing).

Tests that help diagnose idiopathic pulmonary fibrosis include the following:

When to seek urgent medical care

Call for an appointment with your health care provider if you develop a regular cough or shortness of breath.

Treatment options

No known cure exists for idiopathic pulmonary fibrosis. Unfortunately, no medication has been shown to improve the outcome of patients with this condition.

Some patients with advanced pulmonary fibrosis may need a lung transplant.

Where to find medical care for Idiopathic pulmonary fibrosis

Directions to Hospitals Treating Idiopathic pulmonary fibrosis

Prevention of Idiopathic pulmonary fibrosis

Avoiding smoking may help prevent this condition, but how to prevent the cause is not known.

What to expect (Outlook/Prognosis)

Some patients may improve when they are treated with corticosteroids or cytotoxic drugs, but in most people the disease can get worse even with treatment. This worsening can happen quickly, or very slowly.

Possible complications

Sources

http://www.nlm.nih.gov/medlineplus/ency/article/000069.htm


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